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    APC-H2-Ab1/Gallus gallus LYZ (GAMKRHGLDNYRGYSLGN) MHC Tetramer (CAT#: MHC-LC1533)

    This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of LYZ-derived peptide of GAMKRHGLDNYRGYSLGN covering 11-27 and H2-Ab1 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.

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    Custom Production

    MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

    Peptide Sequence *:
    Allele Requested *:
    Antigen Species:
    Antigen Molecule:
    Sequence Position:
    Form Requested *:
    Conjugation *:
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    Comments:

    Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line Hep G2
    Figure 1 IF staining of human cell line Hep G2
    (Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm, the Golgi apparatus & actin filaments.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/66182/1763_E3_3_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human salivary gland
    Figure 2 IHC staining of human salivary gland
    (High expression. RNA expression: 21115.5 nTPM)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_B_3_1_val_selected.jpg
    Figure 3 IHC staining of human skeletal muscle
    Figure 3 IHC staining of human skeletal muscle
    (Low expression. RNA expression: 34.0 nTPM)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_B_3_6_val_selected.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Mucosal lymphoid cells
    Staining: Low
    Intensity: Moderate
    Quantity: <25%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_A_7_3.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in tubules
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_A_9_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Leydig cells
    Staining: Low
    Intensity: Weak
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/55/231_A_5_6.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Non-germinal center cells
    Staining: Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_A_7_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enriched (OE19)
    Figure 8 RNA cell line category: Cell line enriched (OE19)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000090382-LYZ

    Specifications

    • Allele
    • H2-Ab1
    • Class
    • Class II
    • MHC Species
    • Mouse
    • Antigen
    • LYZ
    • Antigen Species
    • Gallus gallus
    • Peptide
    • GAMKRHGLDNYRGYSLGN
    • Range
    • 11-27
    • Conjugate
    • APC
    • Application
    • FCM

    Target

    • Antigen Introduction
    • Lysozyme is abundant in secretions including tears, saliva, human milk, and mucus. It is also present in cytoplasmic granules of the macrophages and the polymorphonuclear neutrophils (PMNs). Large amounts of lysozyme can be found in egg white. C-type lysozymes are closely related to alpha-lactalbumin in sequence and structure, making them part of the same family.
    • Alternative Names
    • LYZ; lysozyme; LYZC

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    Please select product type
    IgG Antibodies ScFv Antibodies Single Domain Antibodies Fab Antibodies Humanized Antibodies Mouse Antibodies Human Antibodies MHC Tetramers for Other Applications Rabbit Monoclonal Antibodies IHC Kits & Antibodies
    CAT Product Name Application Type
    MOB-3387z Mouse Anti-LYZ Recombinant Antibody (clone 39H8) WB, FC, ICC, IF, IHC Mouse IgG2a
    MOB-1014MZ Mouse Anti-LYZ Recombinant Antibody (clone BGN/06/961) ELISA, WB Mouse IgG2a
    MOB-174CQ Mouse Anti-Lysozyme Antibody (HYHEL-10) ELISA Mouse IgG1, κ
    MOB-132YJL Mouse Anti-LYZ Recombinant Antibody (clone muHYHEL-10) WB, IHC, FuncS Mouse IgG1, κ
    ZG-0532F Mouse Anti-LYZ Recombinant Antibody (clone LZ-2) FC Mouse IgG1

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