Human Anti-LYZ Recombinant Antibody (clone HYHEL-10) (CAT#: PABL-267)

Recombinant Human Antibody (HYHEL-10) is capable of binding to Lysozyme, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-Lysozyme mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-Lysozyme mAb and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.

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Figure 1 Comparison of the effects of mutations to alanine in the HEWL epitope on the destabilization of the F9.13.7 (shaded bars) and HyHEL-10 (speckled bars) lysozyme complexes.

Pons, J., Stratton, J. R., & Kirsch, J. F. (2002). How do two unrelated antibodies, HyHEL‐10 and F9. 13.7, recognize the same epitope of hen egg‐white lysozyme?. Protein Science,11(10), 2308-2315.


Specifications

  • Immunogen
  • Chicken lysozyme (renal amyloidosis)
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • Human IgG
  • Specificity
  • Chicken LYZ
  • Species Reactivity
  • Chicken
  • Clone
  • HYHEL-10
  • Applications
  • WB, IHC, FuncS

Target

  • Alternative Names
  • LYZ; lysozyme (renal amyloidosis); 1; LYZC; lysozyme C; dystrophin; allergen Gal d IV; egg white lysozyme; 4-beta-N-acetylmuramidase C; 1,4-beta-N-acetylmuramidase C

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Recombinant Antibody

CAT Product Name Application Type
PABL-268 Mouse Anti-LYZ Recombinant Antibody (clone HYHEL-63) WB, ELISA, FuncS Mouse IgG
PABZ-015 Mouse Anti-LYZ Recombinant Antibody (clone HyHEL-5) WB, FuncS Mouse IgG
PABZ-022 Mouse Anti-LYZ Recombinant Antibody (clone D44.1) WB, IF, FuncS Mouse IgG
PABW-022 Human Anti-LYZ Recombinant Antibody (clone dAb HEL4) ELISA Human IgG
PABC-023 Recombinant Mouse Anti-Chicken LYZ Antibody (F10.6.6) WB, IF, FuncS IgG

Single-domain Antibody

CAT Product Name Application Type
PNBL-036 Recombinant Anti-Chicken LYZ VHH Single Domain Antibody (1D2L19) WB, FuncS Llama VHH
PNBL-051 Recombinant Anti-Chicken LYZ VHH Single Domain Antibody (cAbBCII-10) ELISA Llama VHH
PNBL-052 Recombinant Anti-LYZ (D67H) VHH Single Domain Antibody (cAb-HuL6) WB, ELISA, FuncS Llama VHH
PNBL-053 Recombinant Anti-Chicken LYZ VHH Single Domain Antibody (cAb-Lys2) WB, ELISA, FuncS Llama VHH
PNBL-054 Recombinant Anti-Chicken LYZ VHH Single Domain Antibody (cAb-Lys3) WB, FuncS Llama VHH

Fab Fragment Antibody

CAT Product Name Application Type
PFBZ-015 Mouse Anti-LYZ Recombinant Antibody (clone HyHEL-5); Fab Fragment WB, FuncS Mouse Fab
PFBZ-022 Mouse Anti-LYZ Recombinant Antibody (clone D44.1); Fab Fragment WB, IF, FuncS Mouse Fab
PFBW-022 Human Anti-LYZ Recombinant Antibody (clone dAb HEL4); Fab Fragment ELISA Human Fab
PFBC-023 Mouse Anti-LYZ Recombinant Antibody (clone F10.6.6); Fab Fragment WB, IF, FuncS Mouse Fab
PFBZ-023 Mouse Anti-LYZ Recombinant Antibody (clone F9.13.7); Fab Fragment WB, IHC, IF, FuncS Mouse Fab

scFv Fragment Antibody

CAT Product Name Application Type
PSBW-128 Recombinant Mouse Anti-Turkey LYZ Antibody scFv Fragment (1F9) ELISA scFv
PSBC-129 Recombinant Mouse Anti-Turkey LYZ Antibody scFv Fragment (HyHEL-10 (SFSF) WB, ELISA scFv
FAMAB-0132-CN-S(P) Recombinant Humanized Anti-LYZ Antibody scFv Fragment (HuD1.3) ELISA, IF Humanized scFv
MOB-111YJL-S(P) Human Anti-LYZ Recombinant Antibody (clone HYHEL-10 Y53D); scFv Fragment ELISA, FC, IHC Human scFv
MOB-112YJL-S(P) Human Anti-LYZ Recombinant Antibody (clone HYHEL-10 Y53D,Y58F); scFv Fragment ELISA, FC, IHC Human scFv

Humanized Antibody

CAT Product Name Application Type
PABX-073 Recombinant Human Anti-Lysozyme Antibody (HuLys) WB, ELISA, FuncS IgG
PABX-073-F (E) Recombinant Human Anti-Lysozyme Antibody Fab Fragment (HuLys) WB, ELISA, FuncS Fab

Human Antibody

CAT Product Name Application Type
PABX-138 Recombinant Human Anti-Lysozyme Antibody WB, Neut, FuncS IgG
PABX-138-S (P) Recombinant Human Anti-Lysozyme Antibody scFv Fragment WB, Neut, FuncS scFv
PABX-139-S (P) Mouse Anti-LYZ Recombinant Antibody; scFv Fragment (PABX-139-S (P)) WB, ELISA, FuncS Mouse scFv
PABX-138-F (E) Recombinant Human Anti-Lysozyme Antibody Fab Fragment WB, Neut, FuncS Fab

Mouse Antibody

CAT Product Name Application Type
PABX-139 Mouse Anti-LYZ Recombinant Antibody (PABX-139) WB, ELISA, FuncS Mouse IgG
PABX-073-S (P) Recombinant Human Anti-Lysozyme Antibody scFv Fragment (HuLys) WB, ELISA, FuncS scFv
PABX-074-S (P) Recombinant Mouse Anti-Lysozyme Antibody scFv Fragment (HyHEL-5) WB, ELISA, FuncS scFv
PABX-074-F (E) Recombinant Mouse Anti-Lysozyme Antibody Fab Fragment (HyHEL-5) WB, ELISA, FuncS Fab
PABX-139-F (E) Mouse Anti-LYZ Recombinant Antibody; Fab Fragment (PABX-139-F (E)) WB, ELISA, FuncS Mouse Fab

MHC Tetramer for Other Applications

CAT Product Name Application Type
MHC-LC1133 PE-H2-Aa/Gallus gallus LYZ (AMKRHGLDNYRGYS) MHC Tetramer FCM
MHC-LC1532 PE-H2-Ab1/Gallus gallus LYZ (GAMKRHGLDNYRGYSLGN) MHC Tetramer FCM
MHC-LC1134 APC-H2-Aa/Gallus gallus LYZ (AMKRHGLDNYRGYS) MHC Tetramer FCM
MHC-LC1533 APC-H2-Ab1/Gallus gallus LYZ (GAMKRHGLDNYRGYSLGN) MHC Tetramer FCM
MHC-LC1534 BV421-H2-Ab1/Gallus gallus LYZ (GAMKRHGLDNYRGYSLGN) MHC Tetramer FCM

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2112 Hi-Affi™ Recombinant Rabbit Anti-LYZ Monoclonal Antibody (DS2112AB) ICC, IHC-P, IP, WB IgG

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For Research Use Only. Not For Clinical Use.

* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
IAImmunoassay
IBImmunoblotting
ICCImmunocytochemistry
IDImmunodiffusion
IFImmunofluorescence
IHCImmunohistochemistry
IHC-FrImmunohistochemistry-Frozen
IHC-PImmunohistochemistry-Paraffin
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
Live cell imagingLive cell imaging
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
MultiplexMultiplex bead-based assay
NeutNeutralization
PPProtein Purification
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
TCTissue Culture
TBTurbidimetry
WBWestern Blot

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