Human Anti-ABCB11 Recombinant Antibody (clone Tweed)
CAT#: HPAB-0192-CN
antibody Tweed is an isolated monoclonal antibody Tweed that specifically binds to an extracellular epitope on the N-terminal half of BSEP and modulates BSEP function. antibody Tweed recognizes an epitope present on the C-terminal half of BSEP,
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19035/if_selected.jpg
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Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Human ABCB11
- Species Reactivity
- Human, Rat
- Clone
- Tweed
- Applications
- WB, FC, IF
- Related Disease
- Cancer such as hepatocellular carcinoma and hepatoblastoma
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11; Progressive Familial Intrahepatic Cholestasis 2; ATP-Binding Cassette Sub-Family B Member 11; BSEP; ABC Member 16, MDR/TAP Subfamily; Bile Salt Export Pump; Sister P-Glycoprotein; MDR/TAP Subfamily; ABC Member 16; EC 3.6.3.44; EC 3.6.3; PFIC-2; ABC16; BRIC2; PFIC2; PGY4; SPGP
- Gene ID
- 8647
- UniProt ID
- O95342
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Clone Tweed"
- CAT
- Product Name
See other products for "ABCB11"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2146z | Mouse Anti-ABCB11 Recombinant Antibody (clone 38B10) | WB, ELISA, IF, IHC, IP | Mouse IgG2a, κ |
| HPAB-0190-CN | Human Anti-ABCB11 Recombinant Antibody (clone Batist) | WB, FC, IF | Human IgG1 |
| HPAB-0191-CN | Human Anti-ABCB11 Recombinant Antibody (clone Malimo) | WB, FC, IF | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0010 | Hi-Affi™ Rabbit Anti-ABCB11 Recombinant Antibody (clone DS10AB) | WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0190-CN-S(P) | Human Anti-ABCB11 Recombinant Antibody (clone Batist); scFv Fragment | WB, FC, IF | Human scFv |
| HPAB-0191-CN-S(P) | Human Anti-ABCB11 Recombinant Antibody (clone Malimo); scFv Fragment | WB, FC, IF | Human scFv |
| HPAB-0192-CN-S(P) | Human Anti-ABCB11 Recombinant Antibody (clone Tweed); scFv Fragment | WB, FC, IF | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0190-CN-F(E) | Human Anti-ABCB11 Recombinant Antibody (clone Batist); Fab Fragment | WB, FC, IF | Human Fab |
| HPAB-0191-CN-F(E) | Human Anti-ABCB11 Recombinant Antibody (clone Malimo); Fab Fragment | WB, FC, IF | Human Fab |
| HPAB-0192-CN-F(E) | Human Anti-ABCB11 Recombinant Antibody (clone Tweed); Fab Fragment | WB, FC, IF | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC611 | Recombinant Anti-ABCB11 Vesicular Antibody, EV Displayed (VS-0425-YC611) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY18 | Anti-ABCB11 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC16 | Recombinant Anti-ABCB11 (N-terminus x C-terminus) Biparatopic Antibody, Tandem scFv (Clone Batist x Clone Malimo) | FC, IF, WB | Tandem scFv |
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