1 0
Cart
    Inquiry
    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    Afuco™ Anti-Human ACVRL1 ADCC Recombinant Antibody (PF-03446962), ADCC Enhanced (CAT#: AFC-012CL)

    Anti-ACVRL1 ADCC Enhanced Antibody (PF-03446962) is an ADCC enhanced antibody produced by our Afuco™ platform. PF-03446962, a fully-human monoclonal antibody against transforming growth-factor β (TGFβ) receptor ALK1, in pre-treated patients with urothelial cancer: an open label, single-group, phase 2 trial.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 IHC staining of human cerebral cortex
    Figure 1 IHC staining of human cerebral cortex
    (Immunohistochemical staining of human cerebral cortex shows strong granular cytoplasmic positivity in neuronal cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/ihc_selected.jpg
    Figure 2 Cerebral cortex
    Figure 2 Cerebral cortex
    (Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_B_7_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_A_7_3.jpg
    Figure 4 Gallbladder
    Figure 4 Gallbladder
    (Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_A_5_4.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_A_8_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Elongated or late spermatids Staining: High Intensity: Strong Quantity:>75% Leydig cells Staining: Low Intensity: Weak Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75%)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_A_6_6.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/7041/21213_A_9_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, EFO-21, HUVEC TERT2, TIME)
    Figure 8 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, EFO-21, HUVEC TERT2, TIME)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000139567-ACVRL1

    Specifications

    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • ADCC enhanced antibody
    • Species Reactivity
    • Human
    • Related Disease
    • Urothelial Cancer

    Product Property

    • Purity
    • >95% as determined by analysis by RP-HPLC
    • Storage
    • Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

    Target

    • Alternative Names
    • ACVRL1; activin A receptor type II-like 1; HHT; ALK1; HHT2; ORW2; SKR3; ALK-1; TSR-I; ACVRLK

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "ACVRL1"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Rabbit Monoclonal Antibody Products Human Antibody Products IgG Antibody Products Fab Antibody Products ADCC Enhanced Antibody Products ScFv Antibody Products Antibody Magnetic Beads ScFv-Fc Chimera Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    MOR-0065 Hi-Affi™ Rabbit Anti-ACVRL1 Recombinant Antibody (clone DS65AB) ELISA Rabbit IgG

    Customer Reviews and Q&As

    Submit a review or a question

    There are currently no Customer reviews or questions for AFC-012CL. Click the button above to contact us or submit your feedback about this product.

    Popular products with customers

    Figure 3 Human Anti-MS4A1 Recombinant Antibody (TAB-772) in SDS-PAGE

    Human Anti-MS4A1 Recombinant Antibody (TAB-772) (CAT# TAB-772)
    Application: ELISA, IP, FC, FuncS, Neut, IF, ICC

    Figure 3 Anti-IL12+IL23 Antibody (TAB-103) in Dot Blot

    Anti-Human IL12+IL23 Recombinant Antibody (Briakinumab) (CAT# TAB-103)
    Application: WB, FC, IP, ELISA, Neut, FuncS, IF

    Figure 10 Blockade of PD-1/PD-L1 interaction by anti-PD-1 antibody (Cat# TAB-770) resulted in an increase of IFN-γ production.

    Anti-PDCD1 Recombinant Antibody (TAB-770) (CAT# TAB-770)
    Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

    Figure 2 Anti-CAIX/CA9 Antibody (TAB-707) in WB

    Anti-CAIX/CA9 Recombinant Antibody (Girentuximab) (CAT# TAB-707)
    Application: WB, FuncS, IF, Neut, ELISA, FC, IP

    Figure 4 Anti-Human IAV HA Recombinant Antibody (TAB-705)-Fc silenced in ELISA

    Anti-αvβ3 Integrin Recombinant Antibody (TAB-705) (CAT# TAB-705)
    Application: FC, IP, ELISA, Neut, FuncS, IF, IHC

    Figure 3 Anti-Human SPP1 Antibody (TAB-582CL) in DB

    Anti-Human SPP1 Recombinant Antibody (ASK8007) (CAT# TAB-582CL)
    Application:

    Figure 3 Anti-Human CD41 Recombinant Antibody (TP-100CL) in DB

    Abciximab (CAT# TP-100CL)
    Application:

    Figure 5 Recombinant Human Anti-IAV HA Antibody (5J8) (PABL-207) in Dot Blot

    Recombinant Human Anti-IAV HA Antibody (5J8) (CAT# PABL-207)
    Application: FuncS

    Figure 2 Mouse Anti-GM3 Recombinant Antibody (PABC-051) in HPLC

    Mouse Anti-GM3 Recombinant Antibody (clone 14F7) (CAT# PABC-051)
    Application: ELISA

    Figure 3 Anti-Human CD34 Recombinant Antibody (TAB-150LC) in ELISA

    Human Anti-CD34 Recombinant Antibody (TAB-150LC) (CAT# TAB-150LC)
    Application: ELISA

    Figure 1 Anti-Human RNF43 Recombinant Antibody (TAB-327CT) in SDS-PAGE

    Mouse Anti-RNF43 Recombinant Antibody (TAB-327CT) (CAT# TAB-327CT)
    Application: WB, ELISA, FC, IHC, IP

    Figure 3 Anti-RABV G Recombinant Antibody (MRO-730LC) in WB

    Anti-RABV G Recombinant Antibody (MRO-730LC) (CAT# MRO-730LC)
    Application: ELISA, Neut, WB

    Figure 2 Recombinant Human Anti-EGFR Antibody (PABX-052) in HPLC

    Recombinant Human Anti-EGFR Antibody (PABX-052) (CAT# PABX-052)
    Application: WB, ELISA, FuncS, IB, FC, SPR, Apop

    Figure 2 Anti-Human CTGF Recombinant Antibody (TAB-443CQ) in HPLC

    Anti-Human CTGF Recombinant Antibody (TAB-443CQ) (CAT# TAB-443CQ)
    Application: ELISA, IHC, FC, IP, IF, Inhib

    Figure 1 Anti-Human CD40 Agonist Antibody (MOB-107LC) in ELISA

    Human Anti-CD40 Recombinant Antibody (MOB-107LC) (CAT# MOB-107LC)
    Application: FC, FuncS, ELISA

    Figure 3 Anti-DPP4 Recombinant Antibody (HPAB-0215-YC) in ELISA

    Human Anti-DPP4 Recombinant Antibody (HPAB-0215-YC) (CAT# HPAB-0215-YC)
    Application: ELISA, Inhib, FuncS

    Figure 2 Recombinant Mouse Anti-HBV preS1/preS2 Antibody (EPAF-0331CQ) in HPLC

    Recombinant Mouse Anti-HBV preS1/preS2 Antibody (mAb 18/7) (CAT# EPAF-0331CQ)
    Application: Neut, WB

    Figure 2 Anti-TMEM30A Recombinant Antibody (PABL-712CQ) in HPLC

    Human Anti-TMEM30A Recombinant Antibody (PABL-712CQ) (CAT# PABL-712CQ)
    Application: ELISA, FC

    Figure 2 Human Anti-HLA-DR4 Recombinant Antibody (HPAB-0826-FY) in HPLC

    Human Anti-HLA-DR4/GAD-555-567 Recombinant Antibody (clone G3H8) (CAT# HPAB-0826-FY)
    Application: FC

    Figure 3 Human Anti-HLA-A*11:01 Recombinant Antibody, APC (PABJ-0146-APC) in full-wavelength scanning analysis.

    Human Anti-HLA-A*11:01 Recombinant Antibody (clone 2E3) (CAT# PABJ-0146)
    Application: ELISA, FC, FuncS

    For Research Use Only. Not For Clinical Use.

    Send Inquiry

    This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

    Go to compare

    Go to compare