Anti-Human CADM1 Recombinant Antibody (AB10) (CAT#: TAB-1448CL)

Figure 1 Results of cell viability studies with several antibodies (squares indicate Antibody-8 and triangles indicate Antibody-10).

Figure 2 Results of cell adhesion studies with Antibody-10 using DU145 cells and Fibronectin.

Figure 3 Results of cell migration studies with Antibody-10 using BxPC3 cells.

Figure 4 The results of the specificity study with AB10, respectively.

The graphs show the signal detected on CHO cells, negative for CADM1 expression (grey), no transfected Clon 139 (dotted grey line), C!on 139 transfected with an siRNA control (grey line), and Clon 139 transfected with siRNA s24325 selected to reduce CADM1 expression (black line).

Figure 5 The signal detected on CHO transfected with each CADM family member after incubation with AB10 and anti-human fluorescence secondary antibody.

A: CADM1; B:CADM2; C: CADM3; D:CADM4

Figure 6 The results of affinity studies to CADM1 by cytometry with AB10 using A375 ceils

The graphs show a representation of concentration of the antibody versus value of FACS Geometric mean.

Figure 1 Anti-Human CADM1 Recombinant Antibody (TAB-1448CL) in SDS-PAGE

Lane M: Marker
Lane 1: TAB-1448CL in non-reduced condition.
Lane 2: TAB-1448CL in reduced condition.

Figure 2 Anti-Human CADM1 Recombinant Antibody (TAB-1448CL) in HPLC

HPLC analysis of TAB-1448CL shows the purity is>95%.