Mouse Anti-CALR Recombinant Antibody (clone 8B2-H6-10.7) (CAT#: HPAB-0271-YC)
The product is an antibody (8B2-H6-10.7) that specifically binds to a mutant calreticulin protein. The antibody provided herein can be used in the diagnosis studies of or therapeutic intervention in myeloid malignancies.
Specific Inquiry
FC
Figure 1 The antibody specifically recognizes the mutant CALR present on the surface of the respective cells.
The antibody from the above mentioned fraction 4 (1 ug/sample) was used to stain Ba/F3 - MPL cells over expressing different CALR constructs. Anti - mouse APC body. FACS analysis was performed.
Specifications
- Immunogen
- A synthetic peptide with the c-terminal end sequence of the mutant calreticulin protein (Sequence -RRKMSPARPRTSCREACLQGWTEA-), conjugated to the Keyhole Limpet Hemocyanin (KLH)
- Host Species
- Mouse
- Type
- Mouse IgG2a, κ
- Specificity
- Human mutant CALR
- Species Reactivity
- Human
- Clone
- 8B2-H6-10.7
- Applications
- FC, WB
- Related Disease
- Myeloid malignancies
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The antibody was validated for Flow Cytometry and Western Blot. For details, refer to Published Data.
Target
- Alternative Names
- Calreticulin; Sicca Syndrome Antigen A (Autoantigen Ro; Calreticulin); Endoplasmic Reticulum Resident Protein 60; Calregulin; ERp60; CRP55; HACBP; Grp60; Epididymis Secretory Sperm Binding Protein Li 99n; Autoantigen Ro; HEL-S-99n; CC1qR; CRTC; SSA; CRT; RO
- Gene ID
- 811
- UniProt ID
- P27797
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0076MZ | Chicken Anti-Calreticulin Polyclonal IgY | IHC | Chicken antibody |
| BRD-0772MZ | Chicken Anti-Calreticulin Polyclonal IgY | Blocking Assay (BLOCK) IHC (Paraffin) (IHC (P)) ICC (ICC) Flow Cytometry (Flow) IHC (IHC) | Chicken antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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