Mouse Anti-CALR Recombinant Antibody (clone 8B2-H6-10.7); scFv Fragment
CAT#: HPAB-0271-YC-S(P)
The product is an antibody that specifically binds to a mutant calreticulin protein. The antibody provided herein can be used in the diagnosis of or therapeutic intervention in myeloid malignancies.
Gene Expression
Subcellular Location
Figure 1 IHC staining of human duodenum
Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19952/ihc_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to Endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/79775/1900_C3_3_blue_red_green.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2242/8396_B_7_5.jpg
Normal Tissue
Figure 4 Thyroid gland
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2242/8396_B_1_5.jpg
RNA Expression
Figure 5 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000179218-CALR
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Specifications
- Immunogen
- A synthetic peptide with the c-terminal end sequence of the mutant calreticulin protein (Sequence -RRKMSPARPRTSCREACLQGWTEA-), conjugated to the Keyhole Limpet Hemocyanin (KLH)
- Host Species
- Mouse
- Type
- Mouse scFv
- Specificity
- Human mutant CALR
- Species Reactivity
- Human
- Clone
- 8B2-H6-10.7
- Applications
- FC, WB
- Related Disease
- Myeloid malignancies
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Calreticulin; Sicca Syndrome Antigen A (Autoantigen Ro; Calreticulin); Endoplasmic Reticulum Resident Protein 60; Calregulin; ERp60; CRP55; HACBP; Grp60; Epididymis Secretory Sperm Binding Protein Li 99n; Autoantigen Ro; HEL-S-99n; CC1qR; CRTC; SSA; CRT; RO
- Gene ID
- 811
- UniProt ID
- P27797
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 8B2-H6-10.7"
- CAT
- Product Name
See other products for "CALR"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0076MZ | Chicken Anti-Calreticulin Polyclonal IgY | IHC | Chicken antibody |
| BRD-0772MZ | Chicken Anti-Calreticulin Polyclonal IgY | Blocking Assay (BLOCK), IHC (Paraffin) (IHC (P)), ICC (ICC), Flow Cytometry (Flow), IHC (IHC) | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1043 | PE-A*02:01/Human CALR (MLLSVPLLLG) MHC Tetramer | FCM | |
| MHC-LC1044 | APC-A*02:01/Human CALR (MLLSVPLLLG) MHC Tetramer | FCM | |
| MHC-LC1045 | BV421-A*02:01/Human CALR (MLLSVPLLLG) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0443 | Hi-Affi™ Rabbit Anti-CALR Recombinant Antibody (clone DS443AB) | WB, IHC, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0271-YC | Mouse Anti-CALR Recombinant Antibody (clone 8B2-H6-10.7) | FC, WB | Mouse IgG2a, κ |
| MRO-0219-CN | Mouse Anti-CALR Recombinant Antibody (clone 7B1) | WB, IHC, IF, FC | Mouse IgG1 |
| MRO-0220-CN | Mouse Anti-CALR Recombinant Antibody (clone 7B2) | WB, IHC, IF, FC | Mouse IgG1 |
| MRO-0221-CN | Rabbit Anti-CALR Recombinant Antibody (clone CBACN-081) | WB, IF, IHC, IP, FC | Rabbit IgG |
| VS3-CJ840 | Rabbit Anti-CALR Recombinant Antibody (VS3-CJ840) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0271-YC-F(E) | Mouse Anti-CALR Recombinant Antibody (clone 8B2-H6-10.7); Fab Fragment | FC, WB | Mouse Fab |
| HPAB-0446-YJ-F(E) | Mouse Anti-CALR Recombinant Antibody (clone FMMU-CRT-10); Fab Fragment | ELISA, WB, IHC, FC | Mouse Fab |
| HPAB-0447-YJ-F(E) | Human Anti-CALR Recombinant Antibody (clone chFMMU-CRT-10); Fab Fragment | ELISA, WB, IHC, FC | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0446-YJ-S(P) | Mouse Anti-CALR Recombinant Antibody (clone FMMU-CRT-10); scFv Fragment | ELISA, WB, IHC, FC | Mouse scFv |
| HPAB-0447-YJ-S(P) | Mouse Anti-CALR Recombinant Antibody (clone chFMMU-CRT-10); scFv Fragment | ELISA, WB, IHC, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC841 | AbPlus™ Anti-CALR Magnetic Beads (VS-0724-YC841) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY61 | Mouse Anti-NHP CALR Recombinant Antibody (clone FMC 75) | WB, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY297 | Anti-CALR Immunohistochemistry Kit | IHC | |
| VS-0525-XY946 | Anti-Mouse CALR Immunohistochemistry Kit | IHC | |
| VS-0525-XY947 | Anti-Human CALR Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC114 | CytoStream™ Rabbit Anti-CALR Recombinant Antibody (VS13-YC114) | WB, ICC, IF, IHC-P, FC, IP | Rabbit IgG |
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