Mouse Anti-CCND1 Recombinant Antibody (clone DCS-6) (CAT#: NEUT-262CQ)
This antibody is a mouse monoclonal antibody that binds specifically to Cyclin D1, and it can neutralize the bioactivity of Cyclin D1.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27802/1667_B12_1_selected.jpg
(Immunofluorescent staining of human cell line BJ shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27802/1667_B12_1_selected.jpg
Figure 2 IHC staining of human esophagus
(Immunohistochemical staining of human esophagus shows strong nuclear positivity in a fraction of basal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24/ihc_selected.jpg
(Immunohistochemical staining of human esophagus shows strong nuclear positivity in a fraction of basal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24/ihc_selected.jpg
Figure 3 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27802/1607_B12_2_red_green.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/27802/1607_B12_2_red_green.jpg
Figure 4 Liver
(Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24/70_A_9_4.jpg
(Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24/70_A_9_4.jpg
Figure 5 Testis
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24/70_A_6_6.jpg
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/24/70_A_6_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (U-266/70, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110092-CCND1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110092-CCND1
Figure 6 RNA cell line category: Cell line enhanced (U-266/70, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110092-CCND1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110092-CCND1
Specifications
- Immunogen
- Recombinant full length protein corresponding to Human Cyclin D1 aa 1-295.
- Host Species
- Mouse
- Type
- Mouse IgG2a, κ
- Specificity
- Neutralizes the activity of Cyclin D1 in vivo
- Species Reactivity
- Mouse, Rat, Human, Monkey
- Clone
- DCS-6
- Applications
- IHC-Fr, WB, Block, IHC-P, IF, FC, IP
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A purified
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Related Resources
Breast Cancer
Hedgehog Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G004R | Anti-Ccnd1 immunotoxin (IgG)-RTA | Cytotoxicity assay, Function study |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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