Human Anti-CD38 Recombinant Antibody; Fab Fragment (HPAB-0301-YC-F(E)) (CAT#: HPAB-0301-YC-F(E))
This product is a recombinant human Fab antibody that recognizes CD38. The Fab fragment of an antibody is capable of binding to antigens independently of the Fc portion. The antibody inhibited tumor cell growth in both prophylactic and therapeutic settings I, similar to the inhibition observed with anti-CD20 antibodies.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A549
(Immunofluorescent staining of human cell line A549 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22132/1126_F5_3_selected.jpg
(Immunofluorescent staining of human cell line A549 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22132/1126_F5_3_selected.jpg
Figure 2 Colon
(Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22132/51753_A_9_3.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22132/51753_A_9_3.jpg
Figure 3 Prostate
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22132/51753_A_1_5.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22132/51753_A_1_5.jpg
Figure 4 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22132/51753_A_7_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/22132/51753_A_7_8.jpg
Figure 5 RNA cell line category: Cell line enhanced (Daudi, Karpas-707, MOLT-4, REH, RPMI-8226, U-266/70, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000004468-CD38
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000004468-CD38
Figure 5 RNA cell line category: Cell line enhanced (Daudi, Karpas-707, MOLT-4, REH, RPMI-8226, U-266/70, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000004468-CD38
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000004468-CD38
Specifications
- Immunogen
- Cells expressing CD38
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human CD38
- Species Reactivity
- Human, Cynomolgus
- Applications
- ELISA, FC, Cyt
- Related Disease
- Inter alia multiple myeloma
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- See the COA
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD38 Molecule; ADP-Ribosyl Cyclase 1; 2-Phospho-Cyclic-ADP-Ribose Transferase; Cyclic ADP-Ribose Hydrolase 1; 2-Phospho-ADP-Ribosyl Cyclase; NAD(+) Nucleosidase; CD38 Antigen (P45); ADPRC 1; 2-Phospho-ADP-Ribosyl Cyclase/2-Phospho-Cyclic-ADP-Ribose Transferase; Ecto-Nicotinamide Adenine Dinucleotide Glycohydrolase; Cluster Of Differentiation 38; CADPr Hydrolase 1; CD38 Antigen; EC 2.4.99.20; EC 3.2.2.6; ADPRC1; T10
- Gene ID
- 952
- UniProt ID
- P28907
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD38"
Select a product category from the dropdown menu below to view related products.
Please select product type
Single Domain Antibody Products
Mouse Antibody Products
Human Antibody Products
Neutralizing Antibody Products
Rabbit Monoclonal Antibody Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
Antibody Magnetic Beads
Flow Cytometry (FC) related Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-079 | Recombinant Anti-Human CD38 VHH Single Domain Antibody | WB, IHC, FC, FuncS | Llama VHH |
| HPAB-0625-CN | Recombinant Bactrian camel Anti-CD38 Single Domain Antibody (HPAB-0625-CN) | ELISA | VHH |
| HPAB-0626-CN | Recombinant Bactrian camel Anti-CD38 Single Domain Antibody (HPAB-0626-CN) | ELISA | VHH |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-0301-YC-F(E). Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: WB, IHC, FC, Cyt, ELISA
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: Neut, ELISA, WB, SPR, IF, EM
-1.png)
Application: ELISA
Application: ELISA, IHC, WB
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
