Human Anti-CXCL13 Recombinant Antibody (clone Ab 1) (CAT#: HPAB-0060-CN)
Anti-CXCL13 antibody inhibits binding of CXCL13 to CXCR5 and is useful for the treatment of disorders associated with CXCL13, including arthritic disorders such as rheumatoid arthritis.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human bone marrow
(Immunohistochemical staining of human bone marrow shows cytoplasmic positivity in hematopoietic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52613/ihc_selected.jpg
(Immunohistochemical staining of human bone marrow shows cytoplasmic positivity in hematopoietic cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52613/ihc_selected.jpg
Figure 2 Cerebral cortex
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52613/126780_B_8_5.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52613/126780_B_8_5.jpg
Figure 3 Colon
(Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52613/126780_A_9_3.jpg
(Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52613/126780_A_9_3.jpg
Figure 4 Kidney
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52613/126780_A_7_5.jpg
(Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52613/126780_A_7_5.jpg
Figure 5 Testis
(Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52613/126780_A_4_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52613/126780_A_4_6.jpg
Figure 6 Bone marrow
(Hematopoietic cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52613/126780_B_5_4.jpg
(Hematopoietic cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/52613/126780_B_5_4.jpg
Figure 7 RNA cell line category: Cell line enhanced (U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000156234-CXCL13
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000156234-CXCL13
Specifications
- Immunogen
- Chemically synthesised biotinylated human CXCL13
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Human CXCL13
- Species Reactivity
- Human, Monkey
- Clone
- Ab 1
- Applications
- FC, ELISA, WB, IF
- Related Disease
- Arthritic disorders such as rheumatoid arthritis
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CXCL13; C-X-C motif chemokine ligand 13; BLC; BCA1; ANGIE; BCA-1; BLR1L; ANGIE2; SCYB13
- Gene ID
- 10563
- UniProt ID
- O43927
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2335z | Mouse Anti-CXCL13 Recombinant Antibody (clone 24G7) | WB, ELISA, FC, IHC, Neut | Mouse IgG1 |
| MOB-0904MZ | Recombinant Mouse Anti-Human CXCL13 Antibody (clone NN0323-23B3) | Neut | Mouse antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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