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    Recombinant Mouse Anti-DENVE Env E (Fusion loop) Antibody (E53 ) (CAT#: PABL-449)

    Recombinant Mouse Antibody (E53 ) is capable of binding to DENVE Env E (Fusion loop) , expressed in Chinese Hamster Ovary cells (CHO). This antibody recognizes an epitope within the fusion loop of the WNV E glycoprotein.

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    • Conjugation:

    • Endotoxin:

    • Purity:

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    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Published Data
    • Datasheet
    • MSDS
    • COA
    Neut

    Figure 1 Time- and temperature-dependent increases in neutralization by antibodies that bind cryptic determinants on themature virion.

    Figure 1 Time- and temperature-dependent increases in neutralization by antibodies that bind cryptic determinants on themature virion.

    Nine serial four-fold dilutions of the DII-fusion loop (fl)-reactive MAb E53 was incubated with mature WNV RVPs for one hour at room temperature to allow binding to reach equilibrium.

    Dowd, K. A., Jost, C. A., Durbin, A. P., Whitehead, S. S., & Pierson, T. C. (2011). A dynamic landscape for antibody binding modulates antibody-mediated neutralization of West Nile virus. PLoS pathogens, 7(6).


    Specifications

    • Immunogen
    • DENV Envelope proteins
    • Host Species
    • Mouse
    • Derivation
    • Mouse
    • Type
    • IgG
    • Specificity
    • Tested positive against native DENV Env
    • Species Reactivity
    • DENV
    • Clone
    • E53
    • Applications
    • Neut

    Product Property

    • Purity
    • >95% by SDS-PAGE and HPLC analysis
    • Storage
    • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

    Applications

    • Application Notes
    • This antibody has been reported for use in Neutralization.

    Target

    • Alternative Names
    • DENV E; Envelope proteins; E proteins

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    Please select product type
    Immunotoxin Products IgG Antibody Products Fab Antibody Products Single Domain Antibody Products ScFv Antibody Products MHC Tetramer Products for Virology
    CAT Product Name Application Type
    AGTO-L012R anti-env immunotoxin 907 (IgG)-RTA Cytotoxicity assay, Functional assay

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