Recombinant Mouse Anti-DENVE Env E (Fusion loop) Antibody (E53 ) (CAT#: PABL-449)
Recombinant Mouse Antibody (E53 ) is capable of binding to DENVE Env E (Fusion loop) , expressed in Chinese Hamster Ovary cells (CHO). This antibody recognizes an epitope within the fusion loop of the WNV E glycoprotein.
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Neut
Figure 1 Time- and temperature-dependent increases in neutralization by antibodies that bind cryptic determinants on themature virion.
Nine serial four-fold dilutions of the DII-fusion loop (fl)-reactive MAb E53 was incubated with mature WNV RVPs for one hour at room temperature to allow binding to reach equilibrium.
Dowd, K. A., Jost, C. A., Durbin, A. P., Whitehead, S. S., & Pierson, T. C. (2011). A dynamic landscape for antibody binding modulates antibody-mediated neutralization of West Nile virus. PLoS pathogens, 7(6).
Specifications
- Immunogen
- DENV Envelope proteins
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native DENV Env
- Species Reactivity
- DENV
- Clone
- E53
- Applications
- Neut
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- This antibody has been reported for use in Neutralization.
Target
- Alternative Names
- DENV E; Envelope proteins; E proteins
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L012R | anti-env immunotoxin 907 (IgG)-RTA | Cytotoxicity assay, Functional assay |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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