Afuco™ Anti-Human DLK1 ADCC Recombinant Antibody (LIV-1205), ADCC Enhanced (CAT#: AFC-203CL)
Anti-DLK1 ADCC Enhanced Antibody (LIV-1205) is an ADCC enhanced antibody produced by our Afuco™ platform. LIV-1205 is a humanized monoclonal antibody targeting cell surface antigen "DLK-1 (Delta-like 1 homolog)" of liver cancer and other solid cancers. DLK-1 is expected to control the proliferation and differentiation of stem cells, progenitor cells, and other immature cells. LIV-1205 have shown potent anti-tumor activity in various cancer models and is expected to have beneficial clinical efficacy.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62262/1219_G12_1_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/62262/1219_G12_1_selected.jpg
Figure 2 IHC staining of human pituitary gland
(Immunohistochemical staining of human pituitary gland shows strong cytoplasmic positivity in anterior lobe.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/ih_additional_tissue/62262/1270_642_200x200.jpg
(Immunohistochemical staining of human pituitary gland shows strong cytoplasmic positivity in anterior lobe.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/ih_additional_tissue/62262/1270_642_200x200.jpg
Figure 3 Kidney
(Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5872/167264_A_8_5.jpg
(Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5872/167264_A_8_5.jpg
Figure 4 Testis
(Leydig cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5872/167264_A_6_6.jpg
(Leydig cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5872/167264_A_6_6.jpg
Figure 5 RNA cell line category: Group enriched (AF22, Hep G2, SH-SY5Y)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000185559-DLK1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000185559-DLK1
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.
Target
- Alternative Names
- DLK1; delta-like 1 homolog (Drosophila); DLK; FA1; ZOG; pG2; DLK-1; PREF1; Delta1; Pref-1; protein delta homolog 1; secredeltin; fetal antigen 1; preadipocyte factor 1
- Gene ID
- 8788
- UniProt ID
- A0A024R6L1
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-282-F(E) | Recombinant Anti-human DLK1 Antibody Fab Fragment | ELISA, FacS, FuncS | Fab |
| MHH-282-F(E) | Recombinant Human Anti-human DLK1 Antibody Fab Fragment | FC, IP, FuncS | Fab |
| HPAB-0789-CN-F(E) | Mouse Anti-DLK1 Recombinant Antibody; Fab Fragment (HPAB-0789-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
| HPAB-0790-CN-F(E) | Human Anti-DLK1 Recombinant Antibody; Fab Fragment (HPAB-0790-CN-F(E)) | ELISA, FC, IHC | Chimeric (mouse/human) Fab |
| HPAB-0791-CN-F(E) | Human Anti-DLK1 Recombinant Antibody; Fab Fragment (HPAB-0791-CN-F(E)) | ELISA, FC, IHC | Humanized Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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