Afuco™ Anti-Human DLK1 ADCC Recombinant Antibody (LIV-1205), ADCC Enhanced
CAT#: AFC-203CL
Anti-DLK1 ADCC Enhanced Antibody (LIV-1205) is an ADCC enhanced antibody produced by our Afuco™ platform. LIV-1205 is a humanized monoclonal antibody targeting cell surface antigen "DLK-1 (Delta-like 1 homolog)" of liver cancer and other solid cancers. DLK-1 is expected to control the proliferation and differentiation of stem cells, progenitor cells, and other immature cells. LIV-1205 have shown potent anti-tumor activity in various cancer models and is expected to have beneficial clinical efficacy.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line SH-SY5Y
Immunofluorescent staining of human cell line SH-SY5Y shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62262/1219_G12_1_selected.jpg
Normal Tissue
Figure 2 IHC staining of human pituitary gland
Immunohistochemical staining of human pituitary gland shows strong cytoplasmic positivity in anterior lobe.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/ih_additional_tissue/62262/1270_642_200x200.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5872/167264_A_8_5.jpg
Normal Tissue
Figure 4 Testis
Leydig cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5872/167264_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (AF22, Hep G2, SH-SY5Y)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000185559-DLK1
❮
❯
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- Store at -20°C for long-term storage. Store at 4°C for up to one month. Avoid freeze/thaw cycles.
Target
- Alternative Names
- DLK1; delta-like 1 homolog (Drosophila); DLK; FA1; ZOG; pG2; DLK-1; PREF1; Delta1; Pref-1; protein delta homolog 1; secredeltin; fetal antigen 1; preadipocyte factor 1
- Gene ID
- 8788
- UniProt ID
- A0A024R6L1
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| TAB-203MZ | Mouse Anti-DLK1 Recombinant Antibody (TAB-203MZ) | FC, FuncS | Mouse IgG2a |
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| TAB-205MZ | Rat Anti-DLK1 Recombinant Antibody (TAB-205MZ) | FC, FuncS | Rat IgG2b |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0789-CN-F(E) | Mouse Anti-DLK1 Recombinant Antibody; Fab Fragment (HPAB-0789-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0790-CN-F(E) | Human Anti-DLK1 Recombinant Antibody; Fab Fragment (HPAB-0790-CN-F(E)) | ELISA, FC, IHC | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0791-CN-F(E) | Human Anti-DLK1 Recombinant Antibody; Fab Fragment (HPAB-0791-CN-F(E)) | ELISA, FC, IHC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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