How long at 4°C can this antibody be kept?

The antibody can remain stable for up to one month at 4°C. It is best to store it at -20°C for extended periods of time.

Which techniques are available for secondary detection?

This antibody can be used with a variety of secondary detection techniques based on the conjugated secondary antibody, such as fluorescence, colorimetric detection, and chemiluminescence.

Does a protocol need to have a blocking step?

Yes, using agents like BSA or non-fat milk in a blocking step helps reduce non-specific binding, which enhances the specificity and clarity of your data.

Afuco™ Anti-Human FCGR2B ADCC Recombinant Antibody (SM201), ADCC Enhanced

CAT#: AFC-255CL

Anti-FCGR2B ADCC Enhanced Antibody (SM201) is an ADCC enhanced antibody produced by our Afuco™ platform. SM201 is an anti-hFcγRIIB antibody not interfering with ligand binding that mediates immune complex dependent inhibition of B cells, it can be used for the treatment of antibody-mediated autoimmune diseases.

Gene Expression

Normal Tissue Figure 1 Placenta

Endothelial cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Hofbauer cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Syncytiotrophoblasts - cell body
Staining: Medium
Intensity: Moderate
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining: High
Intensity: Strong

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7796/18532_A_3_7.jpg

Normal Tissue Figure 2 Lymph node

Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/7796/18532_A_8_8.jpg

RNA Expression Figure 3 RNA cell line category: Cell line enhanced (Daudi, HMC-1, NB-4, RPMI-8226)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000072694-FCGR2B

❮

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Specifications

Host Species
Human

Type
ADCC enhanced antibody

Species Reactivity
Human

Related Disease
Autoimmune Diseases

Product Property

Purity
>95%, by SDS-PAGE with Coomassie Brilliant Blue staining

Storage
Store at –20 or -70°C upon receipt. Divide antibody into aliquots prior usage and avoid multiple freeze-thaw cycles.

Target

Alternative Names
FCGR2B; Fc fragment of IgG, low affinity IIb, receptor (CD32); CD32; FCG2; CD32B; FCGR2; IGFR2; low affinity immunoglobulin gamma Fc region receptor II-b; CDw32; fcRII-b; Fc gamma RIIb; fc-gamma-RIIb; fc-gamma RII-b; igG Fc receptor II-b; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32)

Gene ID
2213

UniProt ID
P31994

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Breast cancer biomarkers at key points during disease progression

Powerful Signal

The antibody is very pure, just as stated. No contaminants or pollutants have been present that could affect the trial's outcomes.

Elevated Clarity

Customer support has addressed all of our concerns regarding this product in a thorough and timely manner.

Outstanding Client Assistance

This antibody is perfect for long-term research initiatives because of its consistency in performance and stability. In our lab, this reagent is dependable.

Q&As

How long at 4°C can this antibody be kept?

A: The antibody can remain stable for up to one month at 4°C. It is best to store it at -20°C for extended periods of time.
Which techniques are available for secondary detection?

A: This antibody can be used with a variety of secondary detection techniques based on the conjugated secondary antibody, such as fluorescence, colorimetric detection, and chemiluminescence.
Does a protocol need to have a blocking step?

A: Yes, using agents like BSA or non-fat milk in a blocking step helps reduce non-specific binding, which enhances the specificity and clarity of your data.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - AFC-255CL.pdf

MSDS

MSDS - AFC-255CL.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

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