Mouse Anti-FGFR1 Recombinant Antibody (clone CBL059)
CAT#: NEUT-827CQ
This antibody is a mouse monoclonal antibody that binds specifically to FGF-R1, and it can neutralize the bioactivity of FGF-R1.
Gene Expression
Normal Tissue
Figure 1 Cerebral cortex
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33614/67230_B_9_5.jpg
Normal Tissue
Figure 2 Colon
Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33614/67230_A_9_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33614/67230_A_8_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/33614/67230_A_6_6.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (AN3-CA, BJ hTERT+)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000077782-FGFR1
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Specifications
- Immunogen
- Recombinant protein corresponding to human FGF-R1
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human FGFR1
- Species Reactivity
- Human
- Clone
- CBL059
- Applications
- Neut, WB
- Conjugate
- Unconjugated
Product Property
- Purification
- Purified with Protein G affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- FGFR1; fibroblast growth factor receptor 1; CEK; FLG; HH2; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1; FGFR1/PLAG1 fusion; proto-oncogene c-Fgr; FMS-like tyrosine kinase 2; hydroxyaryl-protein kinase; fms-related tyrosine kinase 2; heparin-binding growth factor receptor; basic fibroblast growth factor receptor 1
- Gene ID
- 2260
- UniProt ID
- P11362
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Good for Neutralization
We purchased this antibody (clone CBL059) specifically for its validated application in neutralization (Neut) assays. It's a human IgG1 antibody, which is what we required for our functional studies on human FGFR1 signaling. It has performed reliably in our experiments.
FGFR1 Neutralizing Antibody
This is a high-quality reagent for anyone studying FGFR1. It's a recombinant human IgG1 (clone CBL059) expressed in CHO cells. Its validation for WB and, most importantly, neutralization (Neut) assays, makes it a valuable tool for our research into growth factor signaling pathways.
Q&As
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What applications is this anti-FGFR1 antibody validated for?
A: This recombinant human antibody (clone CBL059) is specifically validated for use in WB and Neutralization (Neut) assays. This makes it an ideal reagent for researchers looking to not only detect human FGFR1 in a WB format but also to functionally inhibit its activity in in vitro studies.
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What is the host and clone of this antibody?
A: This is a recombinant human antibody of the IgG1 isotype. The specific clone is CBL059. It is produced in a mammalian CHO (Chinese Hamster Ovary) expression system, ensuring consistency and proper antibody structure for research, especially for sensitive applications like neutralization assays.
View the frequently asked questions answered by Creative Biolabs Support.
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Related Diseases
EGFR Tyrosine Kinase Inhibitor Resistance
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| TAB-053WM | Mouse Anti-FGFR1 Recombinant Antibody (TAB-053WM) | WB, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
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| TAB-054WM | Human Anti-FGFR1 Recombinant Antibody (TAB-054WM) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| TAB-054WM-S(P) | Human Anti-FGFR1 Recombinant Antibody; scFv Fragment (TAB-054WM-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| HPAB-0118-FY-S(P) | Human Anti-FGFR1 Recombinant Antibody; scFv Fragment (HPAB-0118-FY-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
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| HPAB-0118-FY-F(E) | Human Anti-FGFR1 Recombinant Antibody; Fab Fragment (HPAB-0118-FY-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
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| HPAB-N0346-YC-S(P) | Human Anti-FGFR1 Recombinant Antibody scFv Fragment (HPAB-N0346-YC-S(P)) | ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
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| HPAB-N0346-YC-F(E) | Human Anti-FGFR1 Recombinant Antibody Fab Fragment (HPAB-N0346-YC-F(E)) | ELISA, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0485LY-S(P) | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-A7/C6/D9); scFv Fragment | ELISA | Human scFv |
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| HPAB-0486LY-S(P) | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-A9/H10); scFv Fragment | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0485LY-F(E) | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-A7/C6/D9); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0486LY-F(E) | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-A9/H10); Fab Fragment | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
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| HPAB-0487LY-F(E) | Human Anti-FGFR1 Recombinant Antibody (clone 121-R3P1-B1/E12); Fab Fragment | ELISA | Human Fab |
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| CAT | Product Name | Application | Type |
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