Afuco™ Anti-Human FLT4 ADCC Recombinant Antibody (IMC-3C5), ADCC Enhanced
CAT#: AFC-279CL
Anti-FLT4 ADCC Enhanced Antibody (IMC-3C5) is an ADCC enhanced antibody produced by our Afuco™ platform. IMC-3C5 is a human IgG1 monoclonal antibody receptor antagonist designed to bind VEGFR3 and block the binding of VEGF-C and VEGF-D ligands to the receptor, used to treat solid tumors.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEK 293
Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46519/1909_G1_4_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear speckles & plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/99/if_selected.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/67906/153589_A_9_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/67906/153589_A_7_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (AN3-CA, BEWO, HEK93, HL-60, HUVEC TERT2, JURKAT, T-47d, TIME)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000037280-FLT4
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Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Lung cancer (non-small cell); Solid Tumors
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Target
- Alternative Names
- FLT4; fms-related tyrosine kinase 4; PCL; FLT41; LMPH1A; VEGFR3; vascular endothelial growth factor receptor 3; FLT-4; VEGFR-3; soluble VEGFR3 variant 1; soluble VEGFR3 variant 2; soluble VEGFR3 variant 3; fms-like tyrosine kinase 4; tyrosine-protein kinase receptor FLT4
- Gene ID
- 2324
- UniProt ID
- P35916
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1490z | Mouse Anti-FLT4 Recombinant Antibody (clone 26D3) | WB, FC, IHC, IP | Mouse IgG2a, κ |
| MOB-2181MZ | Recombinant Mouse Anti-Human FLT4 Antibody | ELISA, WB | Mouse antibody |
| ZG-0353J | Mouse Anti-FLT4 Recombinant Antibody (ZG-0353J) | WB, ELISA | Mouse IgG |
| VS3-XY715 | Mouse Anti-FLT4 Recombinant Antibody (clone 4H4) | ELISA, WB | Mouse IgG1 |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-292CL | Human Anti-FLT4 Recombinant Antibody (TAB-292CL) | ELISA | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-015CQ | Anti-Human FLT4 Recombinant Antibody (9D9F9) | ELISA, FC | |
| TAB-015CQ-S(P) | Anti-Human FLT4 Recombinant Antibody scFv Fragment (9D9F9) | ELISA, FC | |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-850CQ | Rat Anti-Flt4 Recombinant Antibody (clone AFL4) | IHC, Block, ELISA, IP, WB | Rat IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-851CQ | Mouse Anti-Flt4 Recombinant Antibody (clone CBL842) | Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4181 | Hi-Affi™ Rabbit Anti-Flt4 Recombinant Antibody (clone SI258DS) | ELISA | Rabbit IgG |
| MOR-4182 | Hi-Affi™ Rabbit Anti-FLT4 Recombinant Antibody (clone SI259DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY54 | Human Anti-FLT4 scFv-Fc Chimera (VS-0425-FY54) | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC359 | Recombinant Anti-FLT4 Vesicular Antibody, EV Displayed (VS-0425-YC359) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2585 | Anti-FLT4 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2586 | Anti-Mouse FLT4 Immunohistochemistry Kit | IHC |
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