This immunotoxin was achieved by conjugating/fusing the Anti-Fcer1g monoclonal antibody to ricin toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to surface IgE-expressing cells. Then the ricin A chain is incorporated into the cell by receptor-mediated endocytosis, blocking ribosomal protein synthesis and ultimately leading to cell death. It was designed for treatment of periodic (seasonal) allergic.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-3321z | Mouse Anti-FCER1G Recombinant Antibody (clone 43B3) | WB, IP, IF, ELISA | Mouse IgM, κ |
MOB-034CQ | Rabbit Anti-Human FCER1G Antibody | ELISA, WB | Rabbit IgG |
FAMAB-1137CQ | Human Anti-FCER1G Recombinant Antibody (clone IE7) | FC | Human IgG1 |
FAMAB-1138CQ | Human Anti-FCER1G Recombinant Antibody (clone IB10) | Block, FC | Human IgG1 |
VS3-FY267 | Recombinant Mouse Anti-FCER1G Antibody (VS3-FY267) | IHC, IF | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NABL-085 | Recombinant Anti-human Fcer1g VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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