Afuco™ Anti-Human GDF15 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-293CL)
Anti-GDF15 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The monoclonal antibodies that bind and inhibit the activity of human GDF15 can be used to treat body weight loss, including cachexia, associated with the over-expression of human GDF15.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11191/1404_F3_1_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11191/1404_F3_1_selected.jpg
Figure 2 Placenta
(Cytotrophoblasts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Syncytiotrophoblasts - cell body
Staining: High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11191/27866_A_1_7.jpg
(Cytotrophoblasts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Syncytiotrophoblasts - cell body
Staining: High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining: High
Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/11191/27866_A_1_7.jpg
Figure 3 RNA cell line category: Cell line enhanced (BEWO, Hep G2, HHSteC, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130513-GDF15
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130513-GDF15
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cachexia
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.
Target
- Alternative Names
- GDF15; growth differentiation factor 15; PDF; MIC1; PLAB; MIC-1; NAG-1; PTGFB; GDF-15; growth/differentiation factor 15; NRG-1; PTGF-beta; placental TGF-beta; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; prostate differentiation factor; macrophage inhibitory cytokine 1; placental bone morphogenetic protein; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1
- Gene ID
- 9518
- UniProt ID
- Q99988
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "GDF15"
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-391-S(P) | Recombinant Anti-human GDF15 Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| HPAB-M0522-YC-S(P) | Human Anti-GDF15 Recombinant Antibody; scFv Fragment (HPAB-M0522-YC-S(P)) | ELISA, Block | Human scFv |
| HPAB-M0523-YC-S(P) | Human Anti-GDF15 Recombinant Antibody; scFv Fragment (HPAB-M0523-YC-S(P)) | ELISA, Block | Human scFv |
| HPAB-0395-YJ-S(P) | Mouse Anti-GDF15 Recombinant Antibody (clone MBM-12); scFv Fragment | ELISA, Inhib | Mouse scFv |
| HPAB-0396-YJ-S(P) | Mouse Anti-GDF15 Recombinant Antibody (clone MBM-14); scFv Fragment | ELISA, Inhib | Mouse scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0781CL | Anti-Human GDF15 Recombinant Antibody | ELISA, WB | Humanized antibody |
| TAB-0781CL-S(P) | Anti-Human GDF15 Recombinant Antibody scFv Fragment | ELISA, WB | Humanized antibody |
| TAB-0781CL-F(E) | Anti-Human GDF15 Recombinant Antibody Fab Fragment | ELISA, WB | Humanized antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0784CL | Human Anti-GDF15 Recombinant Antibody (TAB-0784CL) | ELISA, FC | Human IgG |
| TAB-0784CL-S(P) | Human Anti-GDF15 Recombinant Antibody; scFv Fragment (TAB-0784CL-S(P)) | ELISA, FC | Human scFv |
| TAB-0784CL-F(E) | Human Anti-GDF15 Recombinant Antibody; Fab Fragment (TAB-0784CL-F(E)) | ELISA, FC | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0782CL-S(P) | Anti-Human GDF15 Recombinant Antibody scFv Fragment (A10.3) | ELISA, FC | |
| TAB-0783CL-S(P) | Anti-Human GDF15 Recombinant Antibody scFv Fragment (B2.2) | ELISA, FC | |
| TAB-0785CL-S(P) | Mouse Anti-GDF15 Recombinant Antibody; scFv Fragment (TAB-0785CL-S(P)) | ELISA, FC, WB | Mouse scFv |
| TAB-0786CL-S(P) | Mouse Anti-GDF15 Recombinant Antibody; scFv Fragment (TAB-0786CL-S(P)) | ELISA, FC, WB | Mouse scFv |
| TAB-0787CL-S(P) | Mouse Anti-GDF15 Recombinant Antibody; scFv Fragment (TAB-0787CL-S(P)) | ELISA, FC, WB | Mouse scFv |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1421 | Hi-Affi™ Rabbit Anti-GDF15 Recombinant Antibody (clone DS1421AB) | WB | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0334-CN-F(E) | Mouse Anti-GDF15 Recombinant Antibody; Fab Fragment (HPAB-0334-CN-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0335-CN-F(E) | Mouse Anti-GDF15 Recombinant Antibody; Fab Fragment (HPAB-0335-CN-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0336-CN-F(E) | Mouse Anti-GDF15 Recombinant Antibody; Fab Fragment (HPAB-0336-CN-F(E)) | ELISA, WB | Mouse Fab |
| HPAB-0337-CN-F(E) | Human Anti-GDF15 Recombinant Antibody; Fab Fragment (HPAB-0337-CN-F(E)) | ELISA, WB | Human Fab |
| HPAB-0338-CN-F(E) | Human Anti-GDF15 Recombinant Antibody; Fab Fragment (HPAB-0338-CN-F(E)) | ELISA, WB | Human Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0522-YC | Human Anti-GDF15 Recombinant Antibody (HPAB-M0522-YC) | ELISA, Block | Human IgG |
| HPAB-M0523-YC | Human Anti-GDF15 Recombinant Antibody (HPAB-M0523-YC) | ELISA, Block | Human IgG |
| HPAB-M0524-YC | Human Anti-GDF15 Recombinant Antibody (HPAB-M0524-YC) | ELISA, Block | Human IgG |
| HPAB-M0525-YC | Human Anti-GDF15 Recombinant Antibody (HPAB-M0525-YC) | ELISA, Block | Human IgG |
| HPAB-M0526-YC | Human Anti-GDF15 Recombinant Antibody (HPAB-M0526-YC) | ELISA, Block | Human IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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