Human Anti-GLP1R Recombinant Antibody (clone 5A10)
CAT#: NS-031CN
Anti-GLP1R antibody can be used for the treatment of diabetes, obesity, neurodegenerative diseases, and complications related to cardiac ischemia and reperfusion injury.
Published Data
Gene Expression
FC
Figure 1 FACS analysis which shows GLP1R specific antibodies derived from whole cell immunization display selective binding for transfected cells displaying the human GLP1R.
FuncS
Figure 2 Monoclonal antibodies 5A10 and 9A10 allosterically enhance intracellular cAMP response of human GLP1R while mAb 2A9 is allosterically inert.
FuncS
Figure 3 Monoclonal antibodies 5A10 and 9A10 maintain allosteric activity between 100 and 1000 picomolar of GLP-1 in an antibody dose-dependent manner.
FuncS
Figure 4 Allosteric antibodies increase the sensitivity of GLP1R while amplifying the magnitude of cAMP response to GLP-1 peptide.
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RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (NTERA-2, SCLC-21H)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000112164-GLP1R
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Specifications
- Immunogen
- KLH-coupled peptide that mimic the extracellular loop of the human GLP-1 receptor
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human GLP1R
- Species Reactivity
- Human
- Clone
- 5A10
- Applications
- ELISA, FC
- Related Disease
- Diabetes
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Flow Cytometry, Functional Assay.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2540z | Mouse Anti-GLP1R Recombinant Antibody (MOB-2540z) | ELISA, WB, IP, IF, IHC, FC | Mouse IgG2b, κ |
| HPAB-0384-YC | Human Anti-GLP1R Recombinant Antibody (HPAB-0384-YC) | ELISA, FC, FuncS | Human IgG |
| HPAB-0385-YC | Mouse Anti-GLP1R Recombinant Antibody (clone m38C2) | FuncS | Mouse IgG |
| HPAB-0386-YC | Human Anti-GLP1R Recombinant Antibody (clone h38C2) | FuncS | Humanized IgG |
| VS4-WK197 | Human Anti-GLP1R Recombinant Antibody (clone 7H7) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2540z-F(E) | Recombinant Anti-Human GLP1R Antibody Fab Fragment | ELISA, FuncS | Fab |
| HPAB-0384-YC-F(E) | Human Anti-GLP1R Recombinant Antibody; Fab Fragment (HPAB-0384-YC-F(E)) | ELISA, FC, FuncS | Human Fab |
| HPAB-0385-YC-F(E) | Mouse Anti-GLP1R Recombinant Antibody (clone m38C2); Fab Fragment | FuncS | Mouse Fab |
| HPAB-0386-YC-F(E) | Human Anti-GLP1R Recombinant Antibody (clone h38C2); Fab Fragment | FuncS | Humanized Fab |
| HPAB-0189CQ-F(E) | Human Anti-GLP1R Recombinant Antibody (clone 3F52); Fab Fragment | ELISA, IHC, Block | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2540z-S(P) | Recombinant Anti-Human GLP1R Antibody scFv Fragment | WB, FC, FuncS | scFv |
| HPAB-0384-YC-S(P) | Human Anti-GLP1R Recombinant Antibody; scFv Fragment (HPAB-0384-YC-S(P)) | ELISA, FC, FuncS | Human scFv |
| HPAB-0385-YC-S(P) | Mouse Anti-GLP1R Recombinant Antibody (clone m38C2); scFv Fragment | FuncS | Mouse scFv |
| HPAB-0386-YC-S(P) | Human Anti-GLP1R Recombinant Antibody (clone h38C2); scFv Fragment | FuncS | Humanized scFv |
| HPAB-1530-FY-F(E) | Human Anti-GLP1R Recombinant Antibody; Fab Fragment (HPAB-1530-FY-F(E)) | ELISA, Inhib, IHC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-145CT | Mouse Anti-GLP1R Recombinant Antibody (TAB-145CT) | ELISA, FC | Mouse IgG1 |
| TAB-145CT-S(P) | Mouse Anti-GLP1R Recombinant Antibody; scFv Fragment (TAB-145CT-S(P)) | ELISA, FC | Mouse scFv |
| TAB-145CT-F(E) | Mouse Anti-GLP1R Recombinant Antibody; Fab Fragment (TAB-145CT-F(E)) | ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-031CN-F(E) | Human Anti-GLP1R Recombinant Antibody (clone 5A10); Fab Fragment | ELISA, FC | Human Fab |
| NS-031CN-S(P) | Human Anti-GLP1R Recombinant Antibody (clone 5A10); scFv Fragment | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC452 | CytoStream™ Rabbit Anti-Glp1r Polyclonal Antibody (VS13-YC452) | WB, ELISA, IHC-P, IHC-Fr, FC, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY111 | Human Anti-GLP1R (clone h38C2) scFv-Fc Chimera | IA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC612 | Recombinant Anti-GLP1R Vesicular Antibody, EV Displayed (VS-0425-YC612) | Block, ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2829 | Anti-GLP1R Immunohistochemistry Kit | IHC | |
| VS-0525-XY2830 | Anti-Mouse GLP1R Immunohistochemistry Kit | IHC |
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