Anti-Human HIF-1alpha Recombinant Antibody (6H4) (CAT#: TAB-082CT)
Recombinant monoclonal antibody (6H4) to HIF-1alpha. The isotype is mouse IgG1. The antibody has been tested in western blot (1/100) with cell Lysates and Immunofluorescence (1/100) assays. This antibody intended for the prophylaxis and treatment studies of Pancreatic cancer, Colorectal cancer.
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WB
Figure 1 Validation of monoclonal antibodies against hydroxylated proline 402 or 564 containing peptides of the HIF-1α ODD region.
Clones 6H4 recognized specifically HIF-1α hydroxylated at proline 402 as demonstrated by Western blotting of lysates of JEG-3 cells transfected with a HIF-1α single or double mutated construct at P402 and/or P564.
Rolfo, A., Many, A., Racano, A., Tal, R., Tagliaferro, A., Ietta, F., ... & Caniggia, I. (2010). Abnormalities in oxygen sensing define early and late onset preeclampsia as distinct pathologies. PloS one, 5(10), e13288.
Specifications
- Host Species
- Mouse
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- 6H4
- Applications
- WB
- Related Disease
- Pancreatic cancer, Colorectal cancer
Applications
- Application Notes
- This antibody has been reported for use in Western Blot.
Target
- Alternative Names
- HIF1; MOP1; PASD8; HIF-1A; bHLHe78; HIF-1alpha; HIF1-ALPHA; HIF-1-alpha
- Gene ID
- 3091
- UniProt ID
- Q16665
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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IgG Antibody Products
Mouse Antibody Products
Rabbit Monoclonal Antibody Products
Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1828z | Mouse Anti-HIF1A Recombinant Antibody (clone 6F11) | WB, ELISA, IF | Mouse IgG1 |
| ZG-0430J | Mouse Anti-HIF1A Recombinant Antibody (ZG-0430J) | WB, IHC, IF, ELISA | Mouse IgG |
| ZG-0038U | Rabbit Anti-HIF1A Recombinant Antibody (clone 5D12) | ELISA, IF | Rabbit IgG |
| VS3-QX510 | Mouse Anti-HIF1A Recombinant Antibody (clone 5H7) | WB, IP, ICC, IHC | Mouse IgG1 |
| VS7-0425-WR34 | Mouse Anti-HIF1A Monoclonal Antibody (VS7-0425-WR34) | WB, IHC-P, IF, ICC, ELISA | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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