Recombinant Human Anti-HIV-1 gp120 Antibody (B13)
CAT#: PABW-153
Recombinant Human Antibody (B13) is capable of binding to HIV-1 gp120, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HIV-1 gp120 mAb and CH1-3 region of human IgG and a light chain (LC) encoding VL from anti-HIV-1 gp120 proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. Unlike other CD4BS antibodies, antibody b13 showed substantial, though reduced, binding to the 109-428 variant. In addition, b13 was able to recognize an outer domain–only variant of gp120.
Specifications
- Immunogen
- HIV-1 gp120 Protein
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Antibody Isotype
- IgG
- Specificity
- Tested positive against native HIV-1 gp120 protein
- Species Reactivity
- HIV-1
- Clone
- B13
- Applications
- Can be useful in applications such as: Neutralization, Flow Cytometry
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Target
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To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# PABW-153, RRID: AB_3714205)
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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