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Recombinant Mouse anti-Human MMP14 Monoclonal antibody (EML768) (CAT#: MOB-1237CT)

Recombinant Mouse monoclonal antibody to Human MMP14, expressed in Chinese Hamster Ovary cells(CHO).


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  • Gene Expression
  • Datasheet
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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HaCaT
Figure 1 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to cytosol & intermediate filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51432/1591_G3_3_selected.jpg
Figure 2 IHC staining of human colon
Figure 2 IHC staining of human colon
(Immunohistochemical staining of human colon shows strong luminal membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51432/134761_A_8_3_selected.jpg
Figure 3 IHC staining of human urinary bladder
Figure 3 IHC staining of human urinary bladder
(Immunohistochemical staining of human urinary bladder shows positivity in stromal cells and plasma.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/ihc_selected.jpg
Figure 4 IF staining of human cell line BJ
Figure 4 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to cytosol & intermediate filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51432/1658_G1_1_blue_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Figure 5 Cerebral cortex
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/24805_B_7_5.jpg
Figure 6 Colon
Figure 6 Colon
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/24805_A_9_3.jpg
Figure 7 Liver
Figure 7 Liver
(Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/24805_A_8_4.jpg
Figure 8 Kidney
Figure 8 Kidney
(Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/24805_A_7_5.jpg
Figure 9 Testis
Figure 9 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/24805_A_6_6.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (ASC diff, HHSteC, HSkMC, hTERT-RPE1)
Figure 10 RNA cell line category: Cell line enhanced (ASC diff, HHSteC, HSkMC, hTERT-RPE1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000157227-MMP14

Specifications

  • Immunogen
  • Purified human recombinant MMP14.
  • Host Species
  • Mouse
  • Specificity
  • It recognizes human MMP14 in western blot without cross reactivity with human MMP1-13, or MMP14-15. Reactivity with Ang1 of other species has not been tested.
  • Species Reactivity
  • Human
  • Clone
  • EML768
  • Applications
  • Used for immunoassay techniques such as: Immunohistochemistry paraffin embedded sections; Western Blot
  • Conjugate
  • Unconjugated

Product Property

  • Purity
  • Protein G purified
  • Format
  • Liquid
  • Concentration
  • 0.2 mg/ml
  • Buffer
  • Preservative: None Constituents: PBS
  • Storage
  • Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

  • Alternative Names
  • MMP14; matrix metallopeptidase 14 (membrane-inserted); MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1; matrix metalloproteinase-14; membrane type 1 metalloprotease; membrane-type-1 matrix metalloproteinase;
  • Function
  • calcium ion binding; integrin binding; metalloendopeptidase activity; peptidase activator activity; protein binding; sequence-specific DNA binding transcription factor activity; zinc ion binding;

Related Resources

  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "MMP14"

Single-domain Antibody

CAT Product Name Application Type
NAB-865-VHH Recombinant Anti-human MMP14 VHH Single Domain Antibody WB, ICC, ChiP, FA, ELISA Llama VHH

Recombinant Antibody

CAT Product Name Application Type
MOB-665 Recombinant Anti-human MMP14 Antibody ELISA, WB, Dot, FuncS IgG
MHH-665 Recombinant Human Anti-human MMP14 Antibody ELISA, WB, FC, FuncS IgG
HPAB-0887-FY Mouse Anti-MMP14 Recombinant Antibody (clone 66C) ELISA Mouse IgG
HPAB-0888-FY Mouse Anti-MMP14 Recombinant Antibody (clone 19B) ELISA, IA Mouse IgG
HPAB-0889-FY Mouse Anti-MMP14 Recombinant Antibody (clone MMP98) ELISA Mouse IgG

scFv Fragment Antibody

CAT Product Name Application Type
MOB-665-S(P) Recombinant Anti-human MMP14 Antibody scFv Fragment FC, Neut, Funcs scFv
HPAB-0260CQ-S(P) Human Anti-MMP14 Recombinant Antibody; scFv Fragment (HPAB-0260CQ-S(P)) ELISA, FC, IHC Human scFv
HPAB-1316-FY-F(E) Human Anti-MMP14 Recombinant Antibody; Fab Fragment (HPAB-1316-FY-F(E)) Activ Human Fab
HPAB-1317-FY-F(E) Human Anti-MMP14 Recombinant Antibody (clone M0030-A04); scFv Fragment ELISA Human scFv
HPAB-1318-FY-F(E) Human Anti-MMP14 Recombinant Antibody (clone M0030-D08); scFv Fragment ELISA Human scFv

Fab Fragment Antibody

CAT Product Name Application Type
MHH-665-F(E) Recombinant Human Anti-human MMP14 Antibody Fab Fragment IP, IF, Biosensors, FuncS Fab
HPAB-0623-WJ-F(E) Human Anti-MMP14 Recombinant Antibody; Fab Fragment (HPAB-0623-WJ-F(E)) ELISA Human Fab
HPAB-0624-WJ-F(E) Human Anti-MMP14 Recombinant Antibody; Fab Fragment (HPAB-0624-WJ-F(E)) ELISA Human Fab
HPAB-0625-WJ-F(E) Human Anti-MMP14 Recombinant Antibody; Fab Fragment (HPAB-0625-WJ-F(E)) ELISA Human Fab
HPAB-0626-WJ-F(E) Human Anti-MMP14 Recombinant Antibody; Fab Fragment (HPAB-0626-WJ-F(E)) ELISA Human Fab

Human Antibody

CAT Product Name Application Type
TAB-531CL Human Anti-MMP14 Recombinant Antibody (TAB-531CL) FuncS Human IgG
TAB-0822CL Human Anti-MMP14 Recombinant Antibody (TAB-0822CL) ELISA, FuncS, FC, IHC Human IgG
TAB-0823CL Human Anti-MMP14 Recombinant Antibody (TAB-0823CL) ELISA Human IgG
TAB-0822CL-S(P) Human Anti-MMP14 Recombinant Antibody; scFv Fragment (TAB-0822CL-S(P)) ELISA, FC, IHC Human scFv
TAB-0823CL-S(P) Human Anti-MMP14 Recombinant Antibody; scFv Fragment (TAB-0823CL-S(P)) ELISA Human scFv

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0370MZ Chicken Anti-MMP14 Polyclonal IgY WB Chicken antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2251 Hi-Affi™ Recombinant Rabbit Anti-MMP14 Monoclonal Antibody (DS2251AB) IHC-P, ICC/IF, FC, IP, WB IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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