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    Recombinant Mouse anti-Human MMP14 Monoclonal antibody (EML768) (CAT#: MOB-1237CT)

    Recombinant Mouse monoclonal antibody to Human MMP14, expressed in Chinese Hamster Ovary cells(CHO).

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    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line HaCaT
    Figure 1 IF staining of human cell line HaCaT
    (Immunofluorescent staining of human cell line HaCaT shows localization to cytosol & intermediate filaments.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51432/1591_G3_3_selected.jpg
    Figure 2 IHC staining of human colon
    Figure 2 IHC staining of human colon
    (Immunohistochemical staining of human colon shows strong luminal membranous positivity in glandular cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51432/134761_A_8_3_selected.jpg
    Figure 3 IHC staining of human urinary bladder
    Figure 3 IHC staining of human urinary bladder
    (Immunohistochemical staining of human urinary bladder shows positivity in stromal cells and plasma.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/ihc_selected.jpg
    Figure 4 IF staining of human cell line BJ
    Figure 4 IF staining of human cell line BJ
    (Immunofluorescent staining of human cell line BJ shows localization to cytosol & intermediate filaments.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51432/1658_G1_1_blue_red_green.jpg
    Normal Tissue
    Figure 5 Cerebral cortex
    Figure 5 Cerebral cortex
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/24805_B_7_5.jpg
    Figure 6 Colon
    Figure 6 Colon
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/24805_A_9_3.jpg
    Figure 7 Liver
    Figure 7 Liver
    (Hepatocytes
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/24805_A_8_4.jpg
    Figure 8 Kidney
    Figure 8 Kidney
    (Cells in glomeruli
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Cells in tubules
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/24805_A_7_5.jpg
    Figure 9 Testis
    Figure 9 Testis
    (Leydig cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/24805_A_6_6.jpg
    RNA Expression
    Figure 10 RNA cell line category: Cell line enhanced (ASC diff, HHSteC, HSkMC, hTERT-RPE1)
    Figure 10 RNA cell line category: Cell line enhanced (ASC diff, HHSteC, HSkMC, hTERT-RPE1)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000157227-MMP14

    Specifications

    • Immunogen
    • Purified human recombinant MMP14.
    • Host Species
    • Mouse
    • Specificity
    • It recognizes human MMP14 in western blot without cross reactivity with human MMP1-13, or MMP14-15. Reactivity with Ang1 of other species has not been tested.
    • Species Reactivity
    • Human
    • Clone
    • EML768
    • Applications
    • Used for immunoassay techniques such as: Immunohistochemistry paraffin embedded sections; Western Blot
    • Conjugate
    • Unconjugated

    Product Property

    • Purity
    • Protein G purified
    • Format
    • Liquid
    • Concentration
    • 0.2 mg/ml
    • Buffer
    • Preservative: None Constituents: PBS
    • Storage
    • Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Target

    • Alternative Names
    • MMP14; matrix metallopeptidase 14 (membrane-inserted); MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1; matrix metalloproteinase-14; membrane type 1 metalloprotease; membrane-type-1 matrix metalloproteinase;
    • Function
    • calcium ion binding; integrin binding; metalloendopeptidase activity; peptidase activator activity; protein binding; sequence-specific DNA binding transcription factor activity; zinc ion binding;

    Related Resources

    • Related Signaling Pathways

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    CAT Product Name Application Type
    NAB-865-VHH Recombinant Anti-human MMP14 VHH Single Domain Antibody WB, ICC, ChiP, FA, ELISA Llama VHH

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