Recombinant Human Anti-human MMP14 Antibody
CAT#: MHH-665
Recombinant Human Antibody prepared by a genetic engineering technique which specifically reacts with Human MMP14, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-MMP14 mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-MMP14 mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to cytosol & intermediate filaments.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51432/1591_G3_3_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human colon
Immunohistochemical staining of human colon shows strong luminal membranous positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51432/134761_A_8_3_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human urinary bladder
Immunohistochemical staining of human urinary bladder shows positivity in stromal cells and plasma.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 4 IF staining of human cell line BJ
Immunofluorescent staining of human cell line BJ shows localization to cytosol & intermediate filaments.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51432/1658_G1_1_blue_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/24805_B_7_5.jpg
Normal Tissue
Figure 6 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/24805_A_9_3.jpg
Normal Tissue
Figure 7 Liver
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/24805_A_8_4.jpg
Normal Tissue
Figure 8 Kidney
Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/24805_A_7_5.jpg
Normal Tissue
Figure 9 Testis
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9918/24805_A_6_6.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (ASC diff, HHSteC, HSkMC, hTERT-RPE1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000157227-MMP14
❮
❯
Specifications
- Immunogen
- Human matrix metallopeptidase 14 (membrane-inserted)
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human matrix metallopeptidase 14 (membrane-inserted)
- Species Reactivity
- Human
- Applications
- Can be useful in applications such as: Enzyme-linked Immunosorbent Assay; Western blot; Flow Cytometry; Functional Study
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions
- Storage
- Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Target
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Related Signaling Pathways
TNF Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-865-VHH | Recombinant Anti-human MMP14 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-665 | Recombinant Anti-human MMP14 Antibody | ELISA, WB, Dot, FuncS | IgG |
| HPAB-0887-FY | Mouse Anti-MMP14 Recombinant Antibody (clone 66C) | ELISA | Mouse IgG |
| HPAB-0888-FY | Mouse Anti-MMP14 Recombinant Antibody (clone 19B) | ELISA, IA | Mouse IgG |
| HPAB-0889-FY | Mouse Anti-MMP14 Recombinant Antibody (clone MMP98) | ELISA | Mouse IgG |
| VS3-CJ1006 | Rabbit Anti-MMP14 Recombinant Antibody (VS3-CJ1006) | WB, ICC, IF, IHC, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-665-F(E) | Recombinant Anti-human MMP14 Antibody Fab Fragment | IF, Neut, FuncS | Fab |
| MHH-665-F(E) | Recombinant Human Anti-human MMP14 Antibody Fab Fragment | IP, IF, Biosensors, FuncS | Fab |
| HPAB-0887-FY-S(P) | Mouse Anti-MMP14 Recombinant Antibody (clone 66C); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0888-FY-S(P) | Mouse Anti-MMP14 Recombinant Antibody (clone 19B); Fab Fragment | ELISA, IA | Mouse Fab |
| HPAB-0889-FY-S(P) | Mouse Anti-MMP14 Recombinant Antibody (clone MMP98); Fab Fragment | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-531CL | Human Anti-MMP14 Recombinant Antibody (TAB-531CL) | FuncS | Human IgG |
| TAB-0822CL | Human Anti-MMP14 Recombinant Antibody (TAB-0822CL) | ELISA, FuncS, FC, IHC | Human IgG |
| TAB-0823CL | Human Anti-MMP14 Recombinant Antibody (TAB-0823CL) | ELISA | Human IgG |
| TAB-0822CL-S(P) | Human Anti-MMP14 Recombinant Antibody; scFv Fragment (TAB-0822CL-S(P)) | ELISA, FC, IHC | Human scFv |
| TAB-0823CL-S(P) | Human Anti-MMP14 Recombinant Antibody; scFv Fragment (TAB-0823CL-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0370MZ | Chicken Anti-MMP14 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2251 | Hi-Affi™ Recombinant Rabbit Anti-MMP14 Monoclonal Antibody (DS2251AB) | IHC-P, ICC, IF, FC, IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0623-WJ-S(P) | Human Anti-MMP14 Recombinant Antibody; scFv Fragment (HPAB-0623-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0624-WJ-S(P) | Human Anti-MMP14 Recombinant Antibody; scFv Fragment (HPAB-0624-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0625-WJ-S(P) | Human Anti-MMP14 Recombinant Antibody; scFv Fragment (HPAB-0625-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0626-WJ-S(P) | Human Anti-MMP14 Recombinant Antibody; scFv Fragment (HPAB-0626-WJ-S(P)) | ELISA | Human scFv |
| HPAB-0627-WJ-S(P) | Human Anti-MMP14 Recombinant Antibody; scFv Fragment (HPAB-0627-WJ-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-CJ1005 | Mouse Anti-MMP14 (C-Terminus) Recombinant Antibody (VS3-CJ1005) | WB | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC295 | Recombinant Anti-MMP14 Vesicular Antibody, EV Displayed (VS-0425-YC295) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4447 | Anti-MMP14 Immunohistochemistry Kit | IHC | |
| VS-0525-XY4448 | Anti-Mouse MMP14 Immunohistochemistry Kit | IHC |
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