Recombinant Mouse anti-Human PDGFRA Monoclonal antibody (27B2) (CAT#: MOB-1274CT)
Recombinant Mouse monoclonal antibody to Human PDGFRA, expressed in Chinese Hamster Ovary cells(CHO).
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm, plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4947/1030_B8_3_selected.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm, plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4947/1030_B8_3_selected.jpg
Figure 2 IHC staining of human bone marrow
(Immunohistochemical staining of human bone marrow shows moderate cytoplasmic positivity in megakaryocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18143/ihc_selected.jpg
(Immunohistochemical staining of human bone marrow shows moderate cytoplasmic positivity in megakaryocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18143/ihc_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18143/43112_B_8_5.jpg
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18143/43112_B_8_5.jpg
Figure 4 Colon
(Enterocytes - Fibroblasts Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18143/43112_A_9_3.jpg
(Enterocytes - Fibroblasts Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18143/43112_A_9_3.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18143/43112_A_7_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18143/43112_A_7_5.jpg
Figure 6 Bone marrow
(Hematopoietic cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18143/43112_B_5_4.jpg
(Hematopoietic cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/18143/43112_B_5_4.jpg
Figure 7 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+, fHDF/TERT166, HHSteC, HSkMC)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134853-PDGFRA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000134853-PDGFRA
Specifications
- Immunogen
- PDGF Receptor alpha-transfected NIH3T3 cells.
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- 27B2
- Applications
- Used for immunoassay techniques such as: Flow Cytometry; Immunocytochemistry
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein A purified
- Format
- Liquid
- Concentration
- 1.0 mg/ml
- Buffer
- Preservative: 15mM Sodium Azide Constituents: PBS, pH 7.4
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- PDGFRA; platelet-derived growth factor receptor, alpha polypeptide; CD140A; PDGFR2; PDGFR-2; RHEPDGFRA; platelet-derived growth factor receptor alpha; PDGF-R-alpha; CD140a antigen; PDGFRA/BCR fusion; CD140 antigen-like family member A; platelet-derived growth factor receptor 2; alpha-type platelet-derived growth factor receptor; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein;
- Gene ID
- 5156
- UniProt ID
- P16234
- Protein Refseq
- NP_006197
- Function
- ATP binding; growth factor binding; nucleotide binding; phosphatidylinositol 3-kinase binding; platelet-derived growth factor alpha-receptor activity; platelet-derived growth factor alpha-receptor activity; platelet-derived growth factor binding; platelet
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-192 | Anti-Human PDGF-R alpha Recombinant Antibody (Olaratumab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 - kappa |
| TAB-878 | Anti-Human CD140a Recombinant Antibody (Tovetumab) | ELISA, FC, IP, FuncS, IF, Neut, WB | IgG2 - kappa |
| TAB-1063CL | Human Anti-PDGFRA Recombinant Antibody (TAB-1063CL) | FuncS | Human antibody |
| TAB-1063CL-S(P) | Human Anti-PDGFRA Recombinant Antibody; scFv Fragment (TAB-1063CL-S(P)) | ELISA | Human scFv |
| TAB-1063CL-F(E) | Human Anti-PDGFRA Recombinant Antibody; Fab Fragment (TAB-1063CL-F(E)) | ELISA | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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