Recombinant Mouse anti-Human ROR2 Monoclonal antibody (EML720)
CAT#: MOB-1051CT
Recombinant Mouse monoclonal antibody to Human ROR2, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IHC staining of human small intestine
Immunohistochemical staining of human small intestine shows distinct cytoplasmic and membranous positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21868/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21868/50700_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21868/50700_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21868/50700_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21868/50700_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21868/50700_A_4_6.jpg
Normal Tissue
Figure 7 Lymph node
Germinal center cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21868/50700_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (AF22, HHSteC, HSkMC, U-266/70, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169071-ROR2/subcellular
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Specifications
- Immunogen
- Recombinant fragment, corresponding to amino acids 34-144 of Human ROR2
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- EML720
- Applications
- Used for immunoassay techniques such as: Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- 1.0 mg/ml
- Buffer
- Preservative: None PBS, pH 7.2
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- ROR2; receptor tyrosine kinase-like orphan receptor 2; BDB; BDB1; NTRKR2; tyrosine-protein kinase transmembrane receptor ROR2; neurotrophic tyrosine kinase receptor-related 2;
- Gene ID
- 4920
- UniProt ID
- Q01974
- Protein Refseq
- NP_004551
- Function
- ATP binding; Wnt-protein binding; frizzled binding; nucleotide binding; receptor activity; transmembrane receptor protein tyrosine kinase activity;
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Related Signaling Pathways
Canonical Wnt Signaling Pathway
Non-Canonical Wnt Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| HPAB-M0201-YC | Rabbit Anti-ROR2 Recombinant Antibody (HPAB-M0201-YC) | ELISA, FC | Rabbit IgG |
| VS3-QX975 | Mouse Anti-ROR2 Recombinant Antibody (clone 10-2D) | WB, FC | Mouse IgG1 |
| VS-0723-WK4 | Human Anti-ROR2 Recombinant Antibody (clone Ozuriftamab) | FC | Chimeric (mouse/human) IgG1 |
| VS13-YC1014 | Rabbit Anti-ROR2 Recombinant Antibody (VS13-YC1014) | IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-860-S(P) | Recombinant Human Anti-human ROR2 Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
| HPAB-1176LY-S(P) | Human Anti-ROR2 Recombinant Antibody; scFv Fragment (HPAB-1176LY-S(P)) | ELISA, FC | Human scfv |
| HPAB-1177LY-S(P) | Human Anti-ROR2 Recombinant Antibody; scFv Fragment (HPAB-1177LY-S(P)) | ELISA, FC | Human scfv |
| HPAB-1178LY-S(P) | Human Anti-ROR2 Recombinant Antibody; scFv Fragment (HPAB-1178LY-S(P)) | ELISA, FC | Human scfv |
| HPAB-1179LY-S(P) | Human Anti-ROR2 Recombinant Antibody; scFv Fragment (HPAB-1179LY-S(P)) | ELISA, FC | Human scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3096 | Hi-Affi™ Recombinant Rabbit Anti-ROR2 Monoclonal Antibody (DS3096AB) | FC, ICC, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-077CN | Human Anti-ROR2 Recombinant Antibody (NS-077CN) | ELISA, FC, FuncS | Human IgG1 |
| NS-077CN-F(E) | Human Anti-ROR2 Recombinant Antibody; Fab Fragment (NS-077CN-F(E)) | ELISA, FC | Human Fab |
| NS-077CN-S(P) | Human Anti-ROR2 Recombinant Antibody; scFv Fragment (NS-077CN-S(P)) | ELISA, FC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1176LY-F(E) | Human Anti-ROR2 Recombinant Antibody; Fab Fragment (HPAB-1176LY-F(E)) | ELISA, FC | Human Fab |
| HPAB-1177LY-F(E) | Human Anti-ROR2 Recombinant Antibody; Fab Fragment (HPAB-1177LY-F(E)) | ELISA, FC | Human Fab |
| HPAB-M0201-YC-F(E) | Rabbit Anti-ROR2 Recombinant Antibody; Fab Fragment (HPAB-M0201-YC-F(E)) | ELISA, FC | Rabbit Fab |
| HPAB-M0202-YC-F(E) | Rabbit Anti-ROR2 Recombinant Antibody; Fab Fragment (HPAB-M0202-YC-F(E)) | ELISA, FC | Rabbit Fab |
| HPAB-M0203-YC-F(E) | Rabbit Anti-ROR2 Recombinant Antibody; Fab Fragment (HPAB-M0203-YC-F(E)) | ELISA, FC | Rabbit Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY189 | CytoStream™ Mouse Anti-ROR2 Recombinant Antibody (VS-0225-XY189) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY35 | Human Anti-ROR2 scFv-Fc Chimera (VS-0325-FY35) | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC437 | Recombinant Anti-ROR2 Vesicular Antibody, EV Displayed (VS-0425-YC437) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6179 | Anti-ROR2 Immunohistochemistry Kit | IHC |
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