Anti-Human TNF beta Recombinant Antibody (TAB-071) (CAT#: TAB-071)
Recombinant monoclonal antibody to TNF beta. It is an immunomodulator. It binds to lymphotoxin alpha.
Specific Inquiry
WB
Figure 1 Anti-Human TNF beta Antibody (TAB-071) in WB
Western blot analysis of TAB-071 was performed with Recombinant Human TNF beta Protein (lane 1, 0.1 μg; lane 2, 0.3 μg; lane 3, 0.6 μg) onto a 12% Tris-HCl polyacrylamide gel. Proteins were transferred to a CN membrane and blocked with 5% skim milk for at least one hour. Membranes were probed with TAB-071 and HRP Goat Anti-Human IgG as a secondary antibody. Chemiluminescent detection was performed.
ELISA
Figure 2 Anti-Human TNF beta Antibody (TAB-071) in ELISA
ELISA analysis of TAB-071 was performed by coating with Recombinant Human TNF beta Protein. Then blocked with BSA, and incubated with Anti-Human TNF beta Antibody (TAB-071). The HRP-conjugated goat anti-human IgG as a secondary antibody. Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.
DB
Figure 3 Anti-Human TNF beta Antibody (TAB-071) in DB
Antigen: Recombinant human TNF beta protein
Antibody incubation concentration: 2ng/μL.
The secondary antibody: HRP-conjugated goat anti-human IgG
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- IgG1 - kappa
- Specificity
- Tested positive against native human antigen.
- Species Reactivity
- Human
- Applications
- Neut, ELISA, IF, IP, FuncS, FC, ICC
- Related Disease
- Rheumatoid arthritis (RA)
Product Property
- Purity
- >95.0% as determined by analysis by SDS-PAGE.
- Storage
- Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Applications
- Application Notes
- The LTA antibody has been reported in applications of PK.
Target
- Alternative Names
- Pateclizumab;1202526-59-7;Anti-LTa;RG7416;MLTA3698A;PRO283698;LTA;lymphotoxin alpha (TNF superfamily, member 1);TNFB;lymphotoxin-alpha;LT;TNFSF1;LT-alpha;TNF-beta;tumor necrosis factor beta;tumor necrosis factor ligand superfamily member 1;
- Gene ID
- 4049
- UniProt ID
- P01374
Related Resources
Please refer to Pateclizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Pateclizumab.
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-2017-sdAb | Recombinant Anti-LTA VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
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Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-071, RRID: AB_3111789)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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