Mouse Anti-IL12B Recombinant Antibody (clone CBL437) (CAT#: NEUT-1167CQ)
This antibody is a mouse monoclonal antibody that binds specifically to IL-12/IL-23 p40, and it can neutralize the bioactivity of IL-12/IL-23 p40.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human tonsil
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in a subset of lymphoid cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40970/ihc_selected.jpg
(Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in a subset of lymphoid cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40970/ihc_selected.jpg
Figure 2 Cerebral cortex
(Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40970/86793_B_7_5.jpg
(Neuropil Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40970/86793_B_7_5.jpg
Figure 3 Colon
(Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40970/86793_A_7_3.jpg
(Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40970/86793_A_7_3.jpg
Figure 4 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40970/86793_A_7_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/40970/86793_A_7_4.jpg
Figure 5 RNA cell line category: Cell line enhanced (SCLC-21H)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113302-IL12B
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113302-IL12B
Specifications
- Immunogen
- Recombinant human IL-12 p40/p35 heterodimer
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human IL12B
- Species Reactivity
- Human
- Clone
- CBL437
- Applications
- Neut
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A or G purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IL12B; interleukin 12B; CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B
- Gene ID
- 3593
- UniProt ID
- P29460
Related Resources
Inflammatory Bowel Diseases
Allograft Rejection
Autoimmune Thyroid Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0779CT | Recombinant Mouse anti-Human IL12B Monoclonal antibody (2-2B5) | ELISA, RIA | |
| HPAB-0066-WJ | Human Anti-IL12B Recombinant Antibody (HPAB-0066-WJ) | ELISA | Human IgG |
| VS-0224-XY23 | Mouse Anti-Canine IL12B Recombinant Antibody (clone YC-11) | WB, IP, IHC, ICC | Mouse IgG |
| VS3-WK1762 | Recombinant Rabbit Anti-IL12B Capture Antibody (clone R03-1X8) | ELISA | Rabbit IgG |
| VS3-WK1763 | Recombinant Rabbit Anti-IL12B Detection Antibody (clone R02-6Z7) | ELISA | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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