Rabbit Anti-IL1RL1 Recombinant Antibody (TAB-225CT)

Name: Rabbit Anti-IL1RL1 Recombinant Antibody (TAB-225CT)
SKU: TAB-225CT
Rating: 5 (1 reviews)

CAT#: TAB-225CT

This product is a recombinant Rabbit antibody that recognizes IL-33R (Interleukin 33 receptor). The antibody was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane, cytosol & focal adhesion sites.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/44_B9_1_selected.jpg

Normal Tissue Figure 2 IHC staining of human placenta

Immunohistochemical staining of human placenta shows membranous and cytoplasmic positivity in trophoblastic cells and stromal cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/ihc_selected.jpg

Normal Tissue Figure 3 IHC staining of human cerebral cortex

Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7917/ihc_selected.jpg

Normal Tissue Figure 5 Colon

Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_7_3.jpg

Normal Tissue Figure 6 Liver

Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_8_4.jpg

Normal Tissue Figure 7 Kidney

Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_8_5.jpg

Normal Tissue Figure 8 Testis

Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_6_6.jpg

Normal Tissue Figure 10 Lymph node

Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_9_8.jpg

RNA Expression Figure 11 RNA cell line category: Group enriched (HHSteC, HMC-1, HUVEC TERT2)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115602-IL1RL1

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Specifications

Immunogen
Soluble human IL-33R fused to Fc region of human IgG

Host Species
Rabbit

Type
Rabbit IgG1

Antibody Isotype
IgG1

Specificity
Human IL-33R (Interleukin 33 receptor)

Species Reactivity
Human

Applications
Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Flow Cytometry; Inhibition

Related Disease
Inflammatory disease

Product Property

Purity
>95% as determined by SDS-PAGE

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants.

Gene ID
9173

UniProt ID
Q01638

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-225CT.pdf

MSDS

MSDS - TAB-225CT.pdf

COA

Certificate of Analysis Lookup

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