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IL1RL1
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- Human Anti-IL1RL1 Recombinant Antibody (HPAB-0051-WJ) (HPAB-0051-WJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC
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- Mouse Anti-IL1RL1 Recombinant Antibody (clone KM1750) (HPAB-A1369-YJ)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: ELISA, Inhib
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- Human Anti-IL1RL1 Recombinant Antibody (HPAB-0120-LS) (HPAB-0120-LS)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: Inhib, FC, IHC
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- Human Anti-IL1RL1 Antibody, mRNA (TAB-411CL-mRNA)
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- Species Reactivity: Human
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- Mouse Anti-IL1RL1 Recombinant Antibody (clone CBL510) (NEUT-1304CQ)
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- Species Reactivity: Human, Primate
- Type: Mouse IgG1
- Application: WB, ELISA, Neut
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- Mouse Anti-IL1RL1 Recombinant Antibody (clone CBL171) (NEUT-1303CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Neut, WB
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- Mouse Anti-IL1RL1 Recombinant Antibody (NEUT-1302CQ) (NEUT-1302CQ)
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- Species Reactivity: Human
- Type: Mouse IgG2
- Application: WB, Neut
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- Rat Anti-Il1rl1 Recombinant Antibody (clone CBL595) (NEUT-1301CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG2b
- Application: FC, CyTOF, ELISA, Neut
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- Rat Anti-Il1rl1 Recombinant Antibody (NEUT-1300CQ) (NEUT-1300CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG1, κ
- Application: FC, Block
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- Anti-Human IL1RL1 Recombinant Antibody (TAB-411CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Antibody
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- Human Anti-IL1RL1 Recombinant Antibody (clone chKM1732) (HPAB-A1372-YJ)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: ELISA, Inhib
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- Mouse Anti-IL1RL1 Recombinant Antibody (clone KM1732) (HPAB-A1371-YJ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, Inhib
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- Human Anti-IL1RL1 Recombinant Antibody (clone chKM1750) (HPAB-A1370-YJ)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1
- Application: ELISA, Inhib
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- Rabbit Anti-IL1RL1 Polyclonal Antibody (MRO-1967-CN) (MRO-1967-CN)
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- Species Reactivity: Human, Mouse, Zebrafish
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Recombinant Anti-human IL1RL1 Antibody (MOB-560)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, IP, FuncS
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- Recombinant Human Anti-human IL1RL1 Antibody scFv Fragment (MHH-560-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FuncS
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- Recombinant Anti-human IL1RL1 Antibody scFv Fragment (MOB-560-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: FC, ELISA, FuncS
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- Human Anti-IL1RL1 Recombinant Antibody; scFv Fragment (HPAB-0120-LS-S(P)) (HPAB-0120-LS-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: Inhib, FC, ELISA
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- Human Anti-IL1RL1 Recombinant Antibody; scFv Fragment (HPAB-0051-WJ-S(P)) (HPAB-0051-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, FC
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- Human Anti-IL1RL1 Recombinant Antibody; Fab Fragment (HPAB-0120-LS-F(E)) (HPAB-0120-LS-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: Inhib, FC, ELISA
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- Human Anti-IL1RL1 Recombinant Antibody; Fab Fragment (HPAB-0051-WJ-F(E)) (HPAB-0051-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FC
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- Recombinant Anti-human IL1RL1 Antibody Fab Fragment (MOB-560-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IF, WB, FuncS
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- Recombinant Human Anti-human IL1RL1 Antibody Fab Fragment (MHH-560-F(E))
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- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: WB, IHC, FuncS
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- Species Reactivity: Human
- Target: IL1RL1
- Host Animal: Human
- Application: ELISA, FC, Cell-uptake
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- Anti-IL1RL1 Immunohistochemistry Kit (VS-0325-XY1119)
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- Species Reactivity: Human, Mouse, Rat
- Target: IL1RL1
- Application: IHC
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- Anti-Human IL1RL1 Immunohistochemistry Kit (VS-0525-XY3508)
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- Species Reactivity: Human
- Target: IL1RL1
- Application: IHC
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- Human Anti-IL1RL1 (clone chKM1732) scFv-Fc Chimera (VS-0425-FY2)
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- Species Reactivity: Human
- Type: Human IgG1, scFv-Fc
- Application: WB, IHC, IP, ELISA, Neut
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants.
Protein class
Candidate cardiovascular disease genes, Enzymes, Plasma proteins
Predicted location
Intracellular, Membrane, Secreted (different isoforms)
Single cell type specificity
Cell type enriched (granulocytes)
Immune cell specificity
Group enriched (basophil, eosinophil)
Cell line specificity
Group enriched (HHSteC, HMC-1, HUVEC TERT2)
Interaction
Interacts with MYD88, IRAK1, IRAK4, and TRAF6. Bound to its ligand IL-33, interacts with IL1RAP to form the minimal interleukin-33 signaling complex with a 1:1:1 stoichiometry. Interacts with KIT (bound to KITLG/SCF). A mast cell-specific KITLG/SCF-induced interleukin-33 signaling complex contains IL1RL1, IL1RAP, KIT and MYD88. Interacts with TMED1 (PubMed:23319592).
Molecular function
Hydrolase, Receptor
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