Human Anti-IL1RL1 Recombinant Antibody (clone C2244) (CAT#: PABL-704)
Recombinant Human Antibody (C2244) is capable of binding to ST2L, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-ST2L mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-ST2L proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane, cytosol & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/44_B9_1_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane, cytosol & focal adhesion sites.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/44_B9_1_selected.jpg
Figure 2 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows membranous and cytoplasmic positivity in trophoblastic cells and stromal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/ihc_selected.jpg
(Immunohistochemical staining of human placenta shows membranous and cytoplasmic positivity in trophoblastic cells and stromal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/ihc_selected.jpg
Figure 3 IHC staining of human cerebral cortex
(Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7917/ihc_selected.jpg
(Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7917/ihc_selected.jpg
Figure 5 Colon
(Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_7_3.jpg
(Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_7_3.jpg
Figure 6 Liver
(Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_8_4.jpg
(Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_8_4.jpg
Figure 7 Kidney
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_8_5.jpg
(Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_8_5.jpg
Figure 8 Testis
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_6_6.jpg
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_6_6.jpg
Figure 10 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_9_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7406/23807_A_9_8.jpg
Figure 11 RNA cell line category: Group enriched (HHSteC, HMC-1, HUVEC TERT2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115602-IL1RL1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115602-IL1RL1
Specifications
- Immunogen
- Human interleukin 1 receptor-like 1
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human IL1RL1
- Species Reactivity
- Human
- Clone
- C2244
- Applications
- WB, IF, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IL1RL1; interleukin 1 receptor-like 1; T1; ST2; DER4; ST2L; ST2V; FIT-1; IL33R; interleukin-1 receptor-like 1; growth stimulation-expressed; interleukin 1 receptor-related protein; homolog of mouse growth stimulation-expressed
- Gene ID
- 9173
- UniProt ID
- Q01638
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-560-F(E) | Recombinant Anti-human IL1RL1 Antibody Fab Fragment | IF, WB, FuncS | Fab |
| MHH-560-F(E) | Recombinant Human Anti-human IL1RL1 Antibody Fab Fragment | WB, IHC, FuncS | Fab |
| PFBL-697 | Human Anti-IL1RL1 Recombinant Antibody (clone C2244); Fab Fragment | WB, IF, FuncS | Human Fab |
| TAB-222CT-F(E) | Mouse Anti-IL1RL1 Recombinant Antibody; Fab Fragment (TAB-222CT-F(E)) | ELISA, Inhib, FC | Mouse Fab |
| HPAB-0120-LS-F(E) | Human Anti-IL1RL1 Recombinant Antibody; Fab Fragment (HPAB-0120-LS-F(E)) | Inhib, FC, ELISA | Humanized Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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