What is the specific fragment type of this antibody?

This antibody is provided as a Fab fragment. It is a recombinant monoclonal antibody fragment specific for the human Interleukin-23 receptor (IL-23R). This format excludes the Fc region, which can be advantageous for reducing non-specific binding in certain assays.

What is the specificity of this antibody?

This antibody specifically binds to the Human IL-23R (Interleukin 23 receptor). It is derived from a humanized sequence and expressed in CHO cells. It has been tested and validated for use in Enzyme-linked immunosorbent assay (ELISA).

Anti-human IL23R Fab Fragment (TAB-630LC-F(E))

CAT#: TAB-630LC-F(E)

This antibody is a recombinant monoclonal antibody Fab fragment specific for human Interleukin-23 receptor (IL-23R), derived from human. It specifically binds to human IL-23R and can be potentially used in the research of inflammatory, autoimmune and proliferative disorders. This product has been tested by Enzyme-linked immunosorbent assay.

Gene Expression

Normal Tissue Figure 1 IHC staining of human bronchus

Immunohistochemical staining of human bronchus shows distinct positivity in a subset of leukocytes.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/ihc_selected.jpg

Normal Tissue Figure 2 Cerebral cortex

Neuronal cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_B_7_5.jpg

Normal Tissue Figure 3 Colon

Endothelial cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_A_9_3.jpg

Normal Tissue Figure 4 Kidney

Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_A_8_5.jpg

Normal Tissue Figure 5 Testis

Leydig cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/56427/131561_A_6_6.jpg

RNA Expression Figure 6 RNA cell line category: Cell line enhanced (HL-60, HMC-1, K-562, U-2197)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000162594-IL23R

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Specifications

Host Species
Human

Derivation
Humanized

Type
Humanized antibody

Antibody Isotype
IgGκ

Specificity
Human

Applications
ELISA

Related Disease
Inflammatory, autoimmune and proliferative disorders.

Target

Alternative Names
IL23R; interleukin 23 receptor; interleukin-23 receptor; IL-23 receptor

Gene ID
149233

UniProt ID
Q5VWK5

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Breast cancer biomarkers at key points during disease progression

High Specificity ELISA

We employed this anti-IL23R Fab fragment in our ELISA assays. It binds specifically to the human receptor subunit and provided clean data. The recombinant nature of the product ensures that we can rely on it for long-term projects without batch variation.

Convenient Fab Format

The Fab fragment format was necessary for our specific experimental setup to study IL-23 signaling without Fc-mediated effects. This product met our requirements perfectly. It was easy to aliquot and store at -20°C for future use.

Q&As

What is the specific fragment type of this antibody?

A: This antibody is provided as a Fab fragment. It is a recombinant monoclonal antibody fragment specific for the human Interleukin-23 receptor (IL-23R). This format excludes the Fc region, which can be advantageous for reducing non-specific binding in certain assays.
What is the specificity of this antibody?

A: This antibody specifically binds to the Human IL-23R (Interleukin 23 receptor). It is derived from a humanized sequence and expressed in CHO cells. It has been tested and validated for use in Enzyme-linked immunosorbent assay (ELISA).

View the frequently asked questions answered by Creative Biolabs Support.

Cite This Product

To accurately reference this product in your publication, please use the following citation information:

(Creative Biolabs Cat# TAB-630LC-F(E), RRID: AB_3714471)

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-630LC-F(E).pdf

MSDS

MSDS - TAB-630LC-F(E).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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