Afuco™ Anti-Human IL2RB ADCC Recombinant Antibody (MiK-Beta-1), ADCC Enhanced
CAT#: AFC-408CL
Anti-IL2RB ADCC Enhanced Antibody (MiK-Beta-1) is an ADCC enhanced antibody produced by our Afuco™ platform. This is a humanized antibody to the IL-2 receptor beta-chain that acts synergistically with humanized anti-TAC. The humanized Mik beta 1 in combination with humanized anti-Tac will provide a new immunosuppressive therapy for the treatment of autoimmune diseases, graft-versus-host disease, and prevention of allograft rejection.
Gene Expression
Normal Tissue
Figure 1 Bone marrow
Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62657/139408_B_5_4.jpg
Normal Tissue
Figure 2 Lymph node
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62657/139408_A_8_8.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enriched (HDLM-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000100385-IL2RB
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Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Autoimmune Diseases
Product Property
- Purity
- 90–95% (SDS-PAGE)
- Storage
- ≤1 year at -20°C.
Target
- Alternative Names
- IL2RB; interleukin 2 receptor, beta; CD122; IL15RB; P70-75; interleukin-2 receptor subunit beta; p75; IL-2RB; CD122 antigen; IL-2R subunit beta; IL-2 receptor subunit beta; interleukin 15 receptor, beta; high affinity IL-2 receptor beta subunit; high affinity IL-2 receptor subunit beta
- Gene ID
- 3560
- UniProt ID
- P14784
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| TAB-637LC-F(E) | Mouse Anti-IL2RB Recombinant Antibody; Fab Fragment (TAB-637LC-F(E)) | ELISA, FC | Mouse Fab |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1366CQ | Rat Anti-Il2rb Recombinant Antibody (NEUT-1366CQ) | Block, FC, IP | Rat IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0249CQ-F(E) | Mouse Anti-IL2RB Recombinant Antibody (clone MIK-BETA 1); Fab Fragment | FC | Mouse Fab |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2114-FY-S(P) | Mouse Anti-IL2RB Recombinant Antibody (clone MAKA41); scFv Fragment | Inhib | Mouse scFv |
| HPAB-1561WJ-S(P) | Human Anti-IL2RB Recombinant Antibody; scFv Fragment (clone A23A41) | ELISA, WB, Neut | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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