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    Afuco™ Anti-Human ITGA2 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-438CL)

    Anti-ITGA2 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The anti-α2 integrin antibodies comprising a heavy chain variable region, a light chain variable region, a human light chain constant region and a variant human IgG1 heavy chain constant region relates to treatment of cancer.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60991/1358_H10_6_selected.jpg
    Figure 2 IF staining of human cell line HaCaT
    Figure 2 IF staining of human cell line HaCaT
    (Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60991/1591_A6_2_red_green.jpg
    Normal Tissue
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_B_7_5.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_9_3.jpg
    Figure 5 Liver
    Figure 5 Liver
    (Cholangiocytes
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_7_4.jpg
    Figure 6 Kidney
    Figure 6 Kidney
    (Cells in glomeruli
    Staining: Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Collecting ducts
    Staining: High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_9_5.jpg
    Figure 7 Testis
    Figure 7 Testis
    (Leydig cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_6_6.jpg
    Figure 8 Endometrium
    Figure 8 Endometrium
    (Glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_B_6_3.jpg
    RNA Expression
    Figure 9 RNA cell line category: Cell line enhanced (BJ hTERT+, HaCaT, hTERT-RPE1, HUVEC TERT2, TIME)
    Figure 9 RNA cell line category: Cell line enhanced (BJ hTERT+, HaCaT, hTERT-RPE1, HUVEC TERT2, TIME)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164171-ITGA2
    Figure 9 RNA cell line category: Cell line enhanced (BJ hTERT+, HaCaT, hTERT-RPE1, HUVEC TERT2, TIME)
    Figure 9 RNA cell line category: Cell line enhanced (BJ hTERT+, HaCaT, hTERT-RPE1, HUVEC TERT2, TIME)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164171-ITGA2

    Specifications

    • Host Species
    • Mouse
    • Type
    • ADCC enhanced antibody
    • Species Reactivity
    • Human
    • Related Disease
    • Cancer

    Product Property

    • Purity
    • Purity>95% by SDS-PAGE
    • Storage
    • Store at -20°C. Avoid multiple freeze/thaw cycles.

    Target

    • Alternative Names
    • ITGA2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); BR; GPIa; CD49B; HPA-5; VLA-2; VLAA2; integrin alpha-2; collagen receptor; platelet antigen Br; platelet glycoprotein GPIa; VLA2 receptor, alpha-2 subunit; CD49 antigen-like family member B; platelet membrane glycoprotein Ia; human platelet alloantigen system 5; very late activation protein 2 receptor, alpha-2 subunit

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "ITGA2"

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    CAT Product Name Application Type
    MOB-1212z Mouse Anti-ITGA2 Recombinant Antibody (clone 26D8) FC, IHC, FuncS Mouse IgG1
    MOB-2261MZ Recombinant Mouse Anti-Human ITGA2 Antibody WB Mouse antibody
    MOB-072CQ Rat Anti-Mouse ITGA2 Antibody FC Rat IgG2b
    FAMAB-1182CQ Mouse Anti-ITGA2 Recombinant Antibody (clone 16B4) IF, FC, BL, Cyt Mouse IgG1
    VS3-CJ711 Rabbit Anti-ITGA2 Recombinant Antibody (VS3-CJ711) WB, ICC, IF, IHC, IP, FC Rabbit IgG

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