Afuco™ Anti-ITGA2 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-251)
CAT#: AFC-TAB-251
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to ITGA2. It is an immunomodulator. It binds to integrin alpha 2
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60991/1358_H10_6_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/60991/1591_A6_2_red_green.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_B_7_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_9_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_7_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_9_5.jpg
Normal Tissue
Figure 7 Testis
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_A_6_6.jpg
Normal Tissue
Figure 8 Endometrium
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63556/141951_B_6_3.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (BJ hTERT+, HaCaT, hTERT-RPE1, HUVEC TERT2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000164171-ITGA2
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Specifications
- Immunogen
- Whole human keratinocytes.
- Host Species
- Human
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- IF, IP, Neut, FuncS, ELISA, FC
- Conjugate
- Unconjugated
- Generic Name
- Vatelizumab
- Related Disease
- Multiple sclerosis (MS)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Vatelizumab"
Anti-Human ITGA2 Recombinant Antibody (Vatelizumab)Recombinant monoclonal antibody to ITGA2. Vatelizumab is an immunomodulator. It binds to integrin alpha 2
DrugMonitor™ Anti-Vatelizumab Antibody (VS-1224-YC1280)Vatelizumab has been involved in trials for ulcerative colitis treatment. The DrugMonitor™ Anti-Vatelizumab Antibody (VS-1224-YC1280) is an anti-drug antibody (ADA) against Vatelizumab. This drug-based antibody is raised in mice immunized with the Vatelizumab. The anti-Vatelizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Vatelizumab in samples.
See other products for "ITGA2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1212z | Mouse Anti-ITGA2 Recombinant Antibody (clone 26D8) | FC, IHC, FuncS | Mouse IgG1 |
| MOB-2261MZ | Recombinant Mouse Anti-Human ITGA2 Antibody | WB | Mouse antibody |
| HPAB-0312-CN | Mouse Anti-ITGA2 Recombinant Antibody (HPAB-0312-CN) | ELISA, IHC, Block | Mouse IgG1, κ |
| HPAB-0313-CN | Human Anti-ITGA2 Recombinant Antibody (HPAB-0313-CN) | ELISA | Chimeric (mouse/human) IgG1, κ |
| HPAB-0314-CN | Human Anti-ITGA2 Recombinant Antibody (HPAB-0314-CN) | ELISA | Humanized IgG4, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-251 | Anti-Human ITGA2 Recombinant Antibody (Vatelizumab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG4 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-714LC | Mouse Anti-ITGA2 Recombinant Antibody (TAB-714LC) | ELISA | Mouse IgG |
| TAB-715LC | Mouse Anti-ITGA2 Recombinant Antibody (TAB-715LC) | ELISA | Mouse IgG |
| TAB-716LC | Mouse Anti-ITGA2 Recombinant Antibody (TAB-716LC) | ELISA | Mouse IgG |
| TAB-714LC-F(E) | Mouse Anti-ITGA2 Recombinant Antibody; Fab Fragment (TAB-714LC-F(E)) | ELISA | Mouse Fab |
| TAB-715LC-F(E) | Mouse Anti-ITGA2 Recombinant Antibody; Fab Fragment (TAB-715LC-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0293MZ | Chicken Anti-ITGA2 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1542CQ | Recombinant Mouse Anti-ITGA2 Antibody (HAS-4) | FC, IHC-Fr, ICC, IP, BL | IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1543CQ | Recombinant Mouse Anti-ITGA2 Antibody (NEUT-1543CQ) | FC, BL, IP, ELISA | IgG1, κ |
| NEUT-1544CQ | Recombinant Armenian Hamster Anti-Itga2 Antibody (HMα2) | FC, IF, IP, BL | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1871 | Hi-Affi™ Recombinant Rabbit Anti-ITGA2 Monoclonal Antibody (DS1871AB) | ICC, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0312-CN-S(P) | Mouse Anti-ITGA2 Recombinant Antibody; scFv Fragment (HPAB-0312-CN-S(P)) | ELISA, IHC, Block | Mouse scFv |
| HPAB-0313-CN-S(P) | Human Anti-ITGA2 Recombinant Antibody; scFv Fragment (HPAB-0313-CN-S(P)) | ELISA | Human scFv |
| HPAB-0314-CN-S(P) | Human Anti-ITGA2 Recombinant Antibody; scFv Fragment (HPAB-0314-CN-S(P)) | ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0312-CN-F(E) | Mouse Anti-ITGA2 Recombinant Antibody; Fab Fragment (HPAB-0312-CN-F(E)) | ELISA, IHC, Block | Mouse Fab |
| HPAB-0313-CN-F(E) | Human Anti-ITGA2 Recombinant Antibody; Fab Fragment (HPAB-0313-CN-F(E)) | ELISA | Human Fab |
| HPAB-0314-CN-F(E) | Human Anti-ITGA2 Recombinant Antibody; Fab Fragment (HPAB-0314-CN-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY158 | AbPlus™ Anti-ITGA2 Magnetic Beads (HAS-4) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY288 | Mouse Anti-NHP ITGA2 Recombinant Antibody (clone AK7) | IHC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY149 | CytoStream™ Mouse Anti-ITGA2 Recombinant Antibody (VS-0225-XY149) | FC | Mouse IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY137 | Human Anti-ITGA2 (clone Vatelizumab) scFv-Fc Chimera | ELISA, FC | Human IgG4, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC196 | Recombinant Anti-ITGA2 Vesicular Antibody, EV Displayed (VS-0425-YC196) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3615 | Anti-ITGA2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3616 | Anti-Mouse ITGA2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3617 | Anti-Human ITGA2 Immunohistochemistry Kit | IHC |
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