Mouse Anti-Il5 Recombinant Antibody (clone CBL612)
CAT#: NEUT-1447CQ
This antibody is a mouse monoclonal antibody that binds specifically to Rat IL-5, and it can neutralize the bioactivity of Rat IL-5.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (Hep G2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000113525-IL5
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Specifications
- Immunogen
- Recombinant rat IL-5
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Rat Il5
- Species Reactivity
- Rat
- Clone
- CBL612
- Applications
- Neut
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A or G purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Neutralizes Rat IL-5
IL-5 is critical for B-cell differentiation, and we needed to block its activity in our rat models. This mouse monoclonal antibody (clone CBL612) specifically binds to Rat IL-5 and effectively neutralizes its bioactivity. It allowed us to confirm the cytokine's role in immunoglobulin secretion.
Specific And Stable
The specificity of this antibody for Rat IL-5 is excellent. We observed no off-target effects in our assays. The antibody is stable at -20°C, and the Protein A/G purification yields a high-concentration product that is easy to dose in our neutralization experiments.
Q&As
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Does this antibody neutralize Rat IL-5?
A: Yes, this Mouse monoclonal antibody (Clone CBL612) binds specifically to Rat IL-5 and can neutralize its bioactivity. IL-5 is a factor that induces terminal differentiation of late-developing B-cells.
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Is this antibody conjugated or unconjugated?
A: This antibody is supplied as Unconjugated. It is a Mouse IgG2b isotype, purified by Protein A or G. It is suitable for Neutralization (Neut) assays. We recommend storing aliquots at -20°C.
View the frequently asked questions answered by Creative Biolabs Support.
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Related Diseases
Asthma
Inflammatory Bowel Diseases
Autoimmune Thyroid Disease
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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