Afuco™ Anti-IL5 ADCC Recombinant Antibody ADCC Enhanced (AFC-TAB-031)
CAT#: AFC-TAB-031
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human IL5. It is a humanized monoclonal antibody that recognizes interleukin-5 (IL-5), and is used to treat certain kinds of asthma and white blood cell diseases.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (Hep G2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000113525-IL5
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Specifications
- Immunogen
- Recombinant human IL5.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Antibody Isotype
- IgG1, κ
- Species Reactivity
- Human
- Applications
- IF, IP, Neut, FuncS, ELISA, FC
- Conjugate
- Unconjugated
- Trade name
- Bosatria
- Generic Name
- Mepolizumab
- Related Disease
- Asthma
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Biosimilar Overview
Please refer to Mepolizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Mepolizumab.
Related Diseases
Asthma
Inflammatory Bowel Diseases
Autoimmune Thyroid Disease
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Mepolizumab"
DrugMonitor™ Anti-Mepolizumab Antibody (VS-1224-YC738)Mepolizumab is a fully-humanized monoclonal IgG1 kappa anti-IL-5 antibody used with other therapies for severe asthma, eosinophilic granulomatosis with polyangiitis, and hypereosinophilic syndrome. The DrugMonitor™ Anti-Mepolizumab Antibody (VS-1224-YC738) is an anti-drug antibody (ADA) against Mepolizumab. This drug-based antibody is raised in mice immunized with the Mepolizumab. The anti-Mepolizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Mepolizumab in samples.
See other products for "IL5"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1202z | Mouse Anti-IL5 Recombinant Antibody (clone 37C3) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-031 | Anti-Human IL5 Recombinant Antibody (TAB-031) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-136 | Anti-Human IL5 Recombinant Antibody (TAB-136) | Neut, ELISA, IF, IP, FuncS, FC, IHC | IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0631CT | Recombinant Mouse anti-Human IL5 Monoclonal antibody (RT-6) | ELISA, ELISPOT, IHC-Fr, Neut, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1437CQ | Mouse Anti-IL5 Recombinant Antibody (clone CBL632) | ELISA, Neut | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1438CQ | Mouse Anti-IL5 Recombinant Antibody (clone CBL420) | Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1439CQ | Rat Anti-IL5 Recombinant Antibody (clone CBL900) | ELISA, FC, IF, Neut, WB | Rat IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1440CQ | Rat Anti-IL5 Recombinant Antibody (clone JES1-39D10) | ELISA, ELISPOT, Neut, ICFC, IHC, WB | Rat IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1441CQ | Rat Anti-IL5 Recombinant Antibody (clone JES1-5A10) | ELISA, ELISPOT, Neut | Rat IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1443CQ | Rat Anti-IL5 Recombinant Antibody (clone TRFK4) | ELISA, Inhib, WB | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0001-CN | Human Anti-IL5 Recombinant Antibody (clone h39D10) | ELISA | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0001-CN-S(P) | Human Anti-IL5 Recombinant Antibody (clone h39D10); scFv Fragment | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0001-CN-F(E) | Human Anti-IL5 Recombinant Antibody (clone h39D10); Fab Fragment | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0359-YC | Human Anti-IL5 Recombinant Antibody (HPAB-N0359-YC) | ELISA, Inhib | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0359-YC-S(P) | Human Anti-IL5 Recombinant Antibody; scFv Fragment (HPAB-N0359-YC-S(P)) | ELISA, Inhib | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0359-YC-F(E) | Human Anti-IL5 Recombinant Antibody; Fab Fragment (HPAB-N0359-YC-F(E)) | ELISA, Inhib | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0250CQ | Human Anti-IL5 Recombinant Antibody (HPAB-0250CQ) | ELISA, Neut, FuncS | Human IgG4, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0250CQ-F(E) | Human Anti-IL5 Recombinant Antibody; Fab Fragment (HPAB-0250CQ-F(E)) | ELISA, Neut, FuncS | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0250CQ-S(P) | Human Anti-IL5 Recombinant Antibody; scFv Fragment (HPAB-0250CQ-S(P)) | ELISA, Neut, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-136 | Afuco™ Anti-IL5 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-136) | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0053-YJ-S(P) | Human Anti-IL5 Recombinant Antibody (clone CMX5-1); scFv Fragment | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0053-YJ-F(E) | Human Anti-IL5 Recombinant Antibody (clone CMX5-1); Fab Fragment | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0875-FY-F(E) | Human Anti-IL5 Recombinant Antibody; Fab Fragment (HPAB-0875-FY-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0875-FY-S(P) | Human Anti-IL5 Recombinant Antibody; scFv Fragment (HPAB-0875-FY-S(P)) | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY144 | CytoStream™ Rat Anti-IL5 Recombinant Antibody (VS-0225-XY144) | FC | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY145 | CytoStream™ Rat Anti-IL5 Recombinant Antibody (clone TRFK5) | FC | Rat IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY206 | Human Anti-IL5 (clone NOL48-1-D5) scFv-Fc Chimera | Inhib, ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC192 | Recombinant Anti-IL5 Eliminating Antibody, pH-Sensitive (VS-0625-YC192) | Antigen-Sweeping In Vivo. | Rat IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC204 | SmartAb™ Recombinant Anti-IL5 pH-dependent Antibody (VS-0825-YC204) | IF, IP, Neut, ELISA, FC, ICC | Human IgG1 kappa |
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