Anti-Human LILRA4 Recombinant Antibody
CAT#: TAB-491CL
Recombinant Human monoclonal antibody expressed in CHO binding to Human LILRA4. Anti-ILT7 antibody binds to plasmacytoid dendritic cells (pDCs), a subset of dendritic cells (DCs). pDCs is known as a major source of IFNα; overproduction of IFNα is considered to be one of the major causes of autoimmune diseases. Anti-ILT7 antibody specifically recognizes and kills pDCs to suppress the IFNα supply, which leads to the improvement of autoimmune disease symptoms.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IHC staining of human lymph node
Immunohistochemical staining of human lymph node shows strong cytoplasmic positivity in non-germinal center cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_8_selected.jpg
Normal Tissue
Figure 2 Colon
Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_3.jpg
Normal Tissue
Figure 3 Kidney
Cells in glomeruli
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_7_5.jpg
Normal Tissue
Figure 4 Testis
Elongated or late spermatids
Staining: High
Intensity: Strong
Quantity:>75%
Round or early spermatids
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/49418/118151_A_5_6.jpg
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Specifications
- Host Species
- Human
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Autoimmune Diseases
Product Property
- Purity
- >95%, by SDS-PAGE with Coomassie Brilliant Blue staining
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- LILRA4; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4; ILT7; CD85g; leukocyte immunoglobulin-like receptor subfamily A member 4; immunoglobulin-like transcript 7; CD85 antigen-like family member G; leukocyte immunoglobulin
- Gene ID
- 23547
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1095CT | Recombinant Mouse anti-Human LILRA4 Monoclonal antibody (28H20.3) | FC | |
| FN-194CQ | Recombinant Mouse Anti-LILRA4 Antibody (17G10.2) | FC, FuncS, IP | Mouse IgG1 |
| HPAB-N0168-YC | Human Anti-LILRA4 Recombinant Antibody (HPAB-N0168-YC) | FC, ELISA, FuncS | Humanized IgG1 |
| VS3-FY2605 | Mouse Anti-LILRA4 Recombinant Antibody (VS3-FY2605) | IHC, FC, ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0168-YC-S(P) | Human Anti-LILRA4 Recombinant Antibody; scFv Fragment (HPAB-N0168-YC-S(P)) | FC, ELISA, FuncS | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0168-YC-F(E) | Human Anti-LILRA4 Recombinant Antibody; Fab Fragment (HPAB-N0168-YC-F(E)) | FC, ELISA, FuncS | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY103 | Human Anti-LILRA4 scFv-Fc Chimera (VS-0325-FY103) | FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC459 | Recombinant Anti-LILRA4 Vesicular Antibody, EV Displayed (VS-0425-YC459) | ELISA, FC, Cell-uptake |
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