Human Anti-LPA Recombinant Antibody (clone hB3); scFv Fragment (CAT#: HPAB-0255-YC-S(P))
LPA is a bioactive lipid mediating multiple cellular responses including proliferation, differentiation, angiogenesis, motility, and protection from apoptosis in a variety of cell types.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IHC staining of human liver
(Immunohistochemical staining of human liver shows moderate cytoplasmic and membranous positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_8_4_selected.jpg
(Immunohistochemical staining of human liver shows moderate cytoplasmic and membranous positivity in hepatocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_8_4_selected.jpg
Figure 2 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows distinc extra cellular and some, weaker membranous and cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16072/ihc_selected.jpg
(Immunohistochemical staining of human kidney shows distinc extra cellular and some, weaker membranous and cytoplasmic positivity in cells in tubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16072/ihc_selected.jpg
Figure 3 Cerebral cortex
(Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_B_7_5.jpg
(Endothelial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_B_7_5.jpg
Figure 4 Colon
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_9_3.jpg
(Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_9_3.jpg
Figure 5 Testis
(Leydig cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_4_6.jpg
(Leydig cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_A_4_6.jpg
Figure 6 Skin
(Epidermal cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_B_6_8.jpg
(Epidermal cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/60604/144547_B_6_8.jpg
Figure 7 Lymph node
(Germinal center cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16072/36402_A_9_8.jpg
(Germinal center cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16072/36402_A_9_8.jpg
Figure 8 RNA cell line category: Cell line enriched (RT4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198670-LPA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000198670-LPA
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized scFv
- Specificity
- Human LPA
- Species Reactivity
- Human
- Clone
- hB3
- Applications
- ELISA, FuncS
- Related Disease
- Fibrosis, Ocular disease
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
scFv Fragment Antibody
Fab Fragment Antibody
Humanized Antibody
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-329 | Recombinant Human Anti-S. aureus LPA Antibody | WB, ELISA, FuncS | IgG |
| HPAB-0253-YC | Mouse Anti-LPA Recombinant Antibody (clone 2D1) | ELISA, WB | Mouse IgG |
| HPAB-0254-YC | Mouse Anti-LPA Recombinant Antibody (clone B3) | ELISA, FuncS | Mouse IgG |
| HPAB-0255-YC | Human Anti-LPA Recombinant Antibody (clone hB3) | ELISA, FuncS | Humanized IgG |
| ZG-0295F | Mouse Anti-LPA Recombinant Antibody (ZG-0295F) | WB, IHC, ELISA | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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