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Mouse Anti-MTDH Recombinant Antibody (clone 1E3); Fab Fragment (CAT#: HPAB-0497-CN-F(E))

A fab anti-AEG-1 antibody 1E3 binds to human AEG-1 with high affinity, which is capable of specifically recognizing AEG-1 in cancer cells.


See more Engineered Antibody products for MTDH
Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/if_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68204/1894_H7_3_selected.jpg
Figure 3 IHC staining of human small intestine
Figure 3 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_4_2_selected.jpg
Figure 4 IHC staining of human cerebral corte
Figure 4 IHC staining of human cerebral corte
(Immunohistochemical staining of human cerebral cortex shows strong positivity.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68204/ihc_selected.jpg
Figure 5 IHC staining of human smooth muscle
Figure 5 IHC staining of human smooth muscle
(Immunohistochemical staining of human smooth muscle shows strong cytoplasmic positivity in smooth muscle cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68205/ihc_selected.jpg
Normal Tissue
Figure 6 Colon
Figure 6 Colon
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_7_3.jpg
Figure 7 Liver
Figure 7 Liver
(Hepatocytes
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_7_4.jpg
Figure 8 Kidney
Figure 8 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_7_5.jpg
Figure 9 Testis
Figure 9 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Spermatogonia cells
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_6_6.jpg
Figure 10 Lymph node
Figure 10 Lymph node
(Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10932/158178_A_8_8.jpg
RNA Expression
Figure 11 RNA cell line category: Low cell line specificity
Figure 11 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000147649-MTDH

Specifications

  • Immunogen
  • Naïve AEG-1
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • Mouse Fab
  • Specificity
  • Human MTDH
  • Species Reactivity
  • Human
  • Clone
  • 1E3
  • Applications
  • WB, ELISA, IHC
  • Related Disease
  • Breast cancer, liver cancer, prostate cancer and melanoma

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • 3D3; AEG1; AEG-1; LYRIC; LYRIC/3D3

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 1E3"

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Recombinant Antibody

CAT Product Name Application Type
MOB-678 Recombinant Anti-human MTDH Antibody ELISA, WB, IF, FuncS IgG
VS3-FY969 Recombinant Mouse Anti-MTDH Antibody (clone 1F3A3) ELISA, WB, IHC, ICC, FC Mouse IgG1
VS3-FY970 Recombinant Mouse Anti-MTDH Antibody (clone 8A4B12) ELISA, WB, IHC, FC Mouse IgG1
VS3-FY971 Recombinant Rabbit Anti-MTDH Antibody (clone R02-7D4) WB, IHC-Fr, IHC-P, ICC, IF Rabbit IgG
VS3-FY972 Recombinant Rabbit Anti-MTDH Antibody (clone R05-5G3) WB, IHC-Fr, IHC-P, ICC, IF, IP Rabbit IgG

Fab Fragment Antibody

CAT Product Name Application Type
MOB-678-F(E) Recombinant Anti-human MTDH Antibody Fab Fragment IP, FuncS Fab
MHH-678-F(E) Recombinant Human Anti-human MTDH Antibody Fab Fragment WB, IF, FuncS Fab

scFv Fragment Antibody

CAT Product Name Application Type
MOB-678-S(P) Recombinant Anti-human MTDH Antibody scFv Fragment ELISA, WB, FuncS scFv
MHH-678-S(P) Recombinant Human Anti-human MTDH Antibody scFv Fragment ELISA, IF, FuncS scFv
HPAB-0497-CN-S(P) Mouse Anti-MTDH Recombinant Antibody (clone 1E3); scFv Fragment WB, ELISA, IHC Mouse scFv

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2316 Hi-Affi™ Recombinant Rabbit Anti-MTDH Monoclonal Antibody (DS2316AB) WB, IHC, ICC IgG
MOR-4646 Hi-Affi™ Recombinant Rabbit Anti-MTDH Monoclonal Antibody (TH159DS) WB, IF, ICC, IHC-P, FC IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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