Recombinant Anti-human Maf Intrabody [Tat]
CAT#: IAB-B020(T)
Recombinant anti-Maf intrabody in fusion with HIV Tat works within cells and is directed against the proto-oncoprotein Maf, expressed in E. coli cells.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human duodenum
Immunohistochemical staining of human duodenum shows moderate nuclear and cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28289/59696_A_9_2_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Glial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10296/32682_B_9_5.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10296/32682_A_8_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10296/32682_A_8_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10296/32682_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10296/32682_A_5_6.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10296/32682_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Group enriched (Karpas-707, RPMI-8226)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000178573-MAF
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Specifications
- Immunogen
- human v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
- Host Species
- human
- Type
- scFv-Tat
- Cell Penetrating Peptide
- TAT
TAT was able to deliver different proteins, such as horseradish peroxidase and RNase A across cell membrane into the cytoplasm in different cell lines in vitro. The size range of proteins with effective delivery is from 30kDa to 120-150kDa. In one study, TAT-fused proteins are rapidly internalized by lipid raft−dependent macropinocytosis using a transducible TAT−Cre recombinase reporter assay on live cells. In another study, a TAT-fused protein was delivered into mitochondria of breast cancer cells and decreased the survival of breast cancer cells, which showed capability of TAT-fusion proteins to modulate mitochondrial function and cell survival. However, very few in vivo studies have succeeded. In one study, in vivo delivery of TAT- or penetratin-crosslinked Fab fragments yielded varied organ distributions and an overall increase in organ retention, which showed tissue localization.
- Species Reactivity
- human
- Applications
- Used for immunoassay techniques such as: Coimmunopricipation; Functional studies
Product Property
- Purity
- >97%, by SDS-PAGE under reducing conditions
- Storage
- ≤1 year at -20°C.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "MAF"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-4079z | Mouse Anti-MAF Recombinant Antibody (clone 35G11) | WB, IP, IF, ELISA | Mouse IgG1, κ |
| MOB-0267CT | Recombinant Mouse anti-Human MAF Monoclonal antibody (EML558) | WB | |
| HPAB-693-FY | Rabbit Anti-MAF Recombinant Antibody (HPAB-693-FY) | WB, SPR | Rabbit IgG |
| VS13-YC681 | Rabbit Anti-MAF Recombinant Antibody (VS13-YC681) | IHC-P | Rabbit IgG |
| VS-0625-FY668 | Mouse Anti-maf Recombinant Antibody (clone 2506W0563) | ELISA | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B020(A) | Recombinant Anti-human Maf Intrabody [(D-Arg)9] | IF, ELISA, FuncS | scFv-(D-Arg)9 |
| IAB-B020(G) | Recombinant Anti-human Maf Intrabody [+36 GFP] | FC, IF, FuncS | scFv-(+36GFP) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2120 | Hi-Affi™ Recombinant Rabbit Anti-MAF Monoclonal Antibody (DS2120AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-693-FY-S(P) | Rabbit Anti-MAF Recombinant Antibody; scFv Fragment (HPAB-693-FY-S(P)) | WB, ELISA | Rabbit scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-693-FY-F(E) | Rabbit Anti-MAF Recombinant Antibody; Fab Fragment (HPAB-693-FY-F(E)) | WB, ELISA | Rabbit Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4164 | Anti-MAF Immunohistochemistry Kit | IHC |
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