Afuco™ Anti-Human NCSTN ADCC Recombinant Antibody (A5226A), ADCC Enhanced (CAT#: AFC-714CL)
Anti-NCSTN ADCC Enhanced Antibody (A5226A) is an ADCC enhanced antibody produced by our Afuco™ platform. A novel monoclonal antibody A5226A is against the extracellular domain of NCT. A5226A by targeting NCT might be a novel therapeutic strategy against cancer caused by aberrant γ-secretase activity and Notch signaling.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70642/1351_B11_2_selected.jpg

(Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54846/ihc_selected.jpg

(Immunohistochemical staining of human stomach shows moderate cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21982/151332_A_5_1_selected.jpg

(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54846/139520_B_9_5.jpg

(Purkinje cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54846/139520_B_9_8.jpg

(Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54846/139520_A_9_3.jpg

(Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21982/151332_A_9_4.jpg

(Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54846/139520_A_7_5.jpg

(Germinal center cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:
Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/21982/151332_A_7_8.jpg

(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000162736-NCSTN
Specifications
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- IP, ICC, FuncS, Inhib, IF
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.
Applications
- Application Notes
- The antibody was validated for Immunoprecipitation, Immunocytochemistry, Function Assay, Inhibition, Immunofluorescence. For details, refer to Published Data.
Target
- Alternative Names
- NCSTN; nicastrin; ATAG1874; anterior pharynx-defective 2
- Gene ID
- 23385
- UniProt ID
- Q92542
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "NCSTN"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-694 | Recombinant Anti-human NCSTN Antibody | ELISA, IP, FuncS | IgG |
MHH-694 | Recombinant Human Anti-human NCSTN Antibody | RIA, IF, FuncS | IgG |
MOB-2454CT | Recombinant Mouse anti-Human NCSTN Monoclonal antibody (nBcdbn) | WB, IHC-P | |
MRO-1095-CN | Recombinant Rabbit Anti-NCSTN Monoclonal Antibody (JG68-33) | WB | Rabbit IgG |
VS3-FY1012 | Recombinant Rabbit Anti-NCSTN Antibody (clone R02-9E6) | WB, IP | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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