Anti-Human NCSTN Recombinant Antibody Fab Fragment (A5201A)
CAT#: TAB-479MZ-F(E)
This novel monoclonal antibody against the extracellular domain of NCT has the neutralization of the γ-secretase activity, which shows a therapeutic potential against proliferation of cancer cells with aberrant activation of the γ-secretase activity-dependent signaling.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/70642/1351_B11_2_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human testis
Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54846/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human stomach
Immunohistochemical staining of human stomach shows moderate cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21982/151332_A_5_1_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54846/139520_B_9_5.jpg
Normal Tissue
Figure 5 Cerebellum
Purkinje cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54846/139520_B_9_8.jpg
Normal Tissue
Figure 6 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54846/139520_A_9_3.jpg
Normal Tissue
Figure 7 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21982/151332_A_9_4.jpg
Normal Tissue
Figure 8 Kidney
Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54846/139520_A_7_5.jpg
Normal Tissue
Figure 9 Lymph node
Germinal center cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:
Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21982/151332_A_7_8.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000162736-NCSTN
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Specifications
- Immunogen
- NCT expressing budded baculovirus
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Human
- Clone
- A5201A
- Applications
- Immunostaining
- Related Disease
- Lung cancer
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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See other products for "NCSTN"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-694 | Recombinant Anti-human NCSTN Antibody | ELISA, IP, FuncS | IgG |
| MHH-694 | Recombinant Human Anti-human NCSTN Antibody | RIA, IF, FuncS | IgG |
| MOB-2454CT | Recombinant Mouse anti-Human NCSTN Monoclonal antibody (nBcdbn) | WB, IHC-P | |
| MRO-1095-CN | Recombinant Rabbit Anti-NCSTN Monoclonal Antibody (JG68-33) | WB | Rabbit IgG |
| VS3-FY1012 | Recombinant Rabbit Anti-NCSTN Antibody (clone R02-9E6) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-694-F(E) | Recombinant Anti-human NCSTN Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
| MHH-694-F(E) | Recombinant Human Anti-human NCSTN Antibody Fab Fragment | ELISA, WB, FC, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-694-S(P) | Recombinant Anti-human NCSTN Antibody scFv Fragment | IF, FC, Biosensors, FuncS | scFv |
| MHH-694-S(P) | Recombinant Human Anti-human NCSTN Antibody scFv Fragment | WB, IF, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-479MZ | Anti-Human NCSTN Recombinant Antibody (A5201A) | ELISA, FuncS, ICC | Human antibody |
| TAB-479MZ-S(P) | Anti-Human NCSTN Recombinant Antibody scFv Fragment (A5201A) | IS | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2386 | Hi-Affi™ Recombinant Rabbit Anti-NCSTN Monoclonal Antibody (DS2386AB) | WB, ICC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1086 | AbPlus™ Anti-NCSTN Magnetic Beads (VS-0724-YC1086) | IP, Protein Purification | |
| VS-0724-YC1160 | AbPlus™ Anti-Ncstn Magnetic Beads (VS-0724-YC1160) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC138 | Recombinant Anti-NCSTN Vesicular Antibody, EV Displayed (VS-0425-YC138) | ELISA, FC, Cell-uptake |
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