Recombinant Human Anti-human NCSTN Antibody
CAT#: MHH-694
Recombinant Human Antibody shows specific binding activity against Human NCSTN, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-NCSTN mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-NCSTN mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/70642/1351_B11_2_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human testis
Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54846/ihc_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IHC staining of human stomach
Immunohistochemical staining of human stomach shows moderate cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21982/151332_A_5_1_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54846/139520_B_9_5.jpg
Normal Tissue
Figure 5 Cerebellum
Purkinje cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54846/139520_B_9_8.jpg
Normal Tissue
Figure 6 Colon
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54846/139520_A_9_3.jpg
Normal Tissue
Figure 7 Liver
Cholangiocytes
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21982/151332_A_9_4.jpg
Normal Tissue
Figure 8 Kidney
Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/54846/139520_A_7_5.jpg
Normal Tissue
Figure 9 Lymph node
Germinal center cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:
Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/21982/151332_A_7_8.jpg
RNA Expression
Figure 10 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000162736-NCSTN
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Specifications
- Immunogen
- Human nicastrin
- Host Species
- Human
- Derivation
- Human
- Type
- IgG
- Specificity
- Tested positive against native Human nicastrin
- Species Reactivity
- Human
- Applications
- Can be useful in applications such as: Radioimmunoassay; Immunofluorescence; Functional Study
Product Property
- Purity
- 95% by HPLC
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Target
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "NCSTN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-694 | Recombinant Anti-human NCSTN Antibody | ELISA, IP, FuncS | IgG |
| MOB-2454CT | Recombinant Mouse anti-Human NCSTN Monoclonal antibody (nBcdbn) | WB, IHC-P | |
| MRO-1095-CN | Recombinant Rabbit Anti-NCSTN Monoclonal Antibody (JG68-33) | WB | Rabbit IgG |
| VS3-FY1012 | Recombinant Rabbit Anti-NCSTN Antibody (clone R02-9E6) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-694-F(E) | Recombinant Anti-human NCSTN Antibody Fab Fragment | WB, ELISA, FuncS | Fab |
| MHH-694-F(E) | Recombinant Human Anti-human NCSTN Antibody Fab Fragment | ELISA, WB, FC, FuncS | Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-694-S(P) | Recombinant Anti-human NCSTN Antibody scFv Fragment | IF, FC, Biosensors, FuncS | scFv |
| MHH-694-S(P) | Recombinant Human Anti-human NCSTN Antibody scFv Fragment | WB, IF, FuncS | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-479MZ | Anti-Human NCSTN Recombinant Antibody (A5201A) | ELISA, FuncS, ICC | Human antibody |
| TAB-479MZ-S(P) | Anti-Human NCSTN Recombinant Antibody scFv Fragment (A5201A) | IS | Human antibody |
| TAB-479MZ-F(E) | Anti-Human NCSTN Recombinant Antibody Fab Fragment (A5201A) | IS | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2386 | Hi-Affi™ Recombinant Rabbit Anti-NCSTN Monoclonal Antibody (DS2386AB) | WB, ICC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1086 | AbPlus™ Anti-NCSTN Magnetic Beads (VS-0724-YC1086) | IP, Protein Purification | |
| VS-0724-YC1160 | AbPlus™ Anti-Ncstn Magnetic Beads (VS-0724-YC1160) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC138 | Recombinant Anti-NCSTN Vesicular Antibody, EV Displayed (VS-0425-YC138) | ELISA, FC, Cell-uptake |
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