Rat Anti-NGF Recombinant Antibody (clone αD11) (CAT#: PABX-146-S (P))

Anti-NGF antibody is a Rat of scFv class that binds to an NGF. The rat monoclonal antibody (mAb) has been shown to bind to NGF with nanomolar affinity and with high specificity and to effectively neutralize its in vitro and in vivo biological functions.

Host: Rat

Isotype: Rat scFv

Applications: Neut, FC, FuncS


Specific Inquiry
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  • Purity:
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  • Published Data
  • Gene Expression
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Figure 1 IP and WB of transgenic and wild-type mice.

IP and WB of cortex extracts from male(M) and female(F) TgProNGF#72 and wild-type (WT) mice. IP on extracts from cortex(CTX) with anti-NGF aD11 antibody, followed by WB with anti-NGF or anti-proNGF antibody, as described in Tiveron et al.(2013). Are presentative WB probed with anti-proNGF(PAb Alomone),(top)or anti-NGFM20 (Santa Cruz)(bottom) is shown. TgproNGF#72 and wild type mice,male and female,were analyzed.

Malerba, F., Paoletti, F., & Cattaneo, A. (2016). NGF and proNGF reciprocal interference in immunoassays: open questions, criticalities, and ways forward. Frontiers in molecular neuroscience, 9, 63.

Figure 2 EmaxNGF Promega:NGFS tandard curves.

NGF standard curves carried out by usingr at mAb Promega(triangles) and mAb aD11(Cattaneoetal.,1988) (squares) as primary antibody.

Malerba, F., Paoletti, F., & Cattaneo, A. (2016). NGF and proNGF reciprocal interference in immunoassays: open questions, criticalities, and ways forward. Frontiers in molecular neuroscience, 9, 63.

Figure 3 SPR analysis-calibration curve sobtained with proNGF and NG Fover the panel of different antibodies.

Different pro NGF concentrations tested on anti-NGFmAb aD11. ConcentrationsinnM(fromtop): 500,333,222,148,98, 65,33,16,8,4,2,1,0.5.

Malerba, F., Paoletti, F., & Cattaneo, A. (2016). NGF and proNGF reciprocal interference in immunoassays: open questions, criticalities, and ways forward. Frontiers in molecular neuroscience, 9, 63.


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Rat
  • Derivation
  • Rat
  • Type
  • Rat scFv
  • Species Reactivity
  • Human
  • Clone
  • αD11
  • Applications
  • Neut, FC, FuncS

Product Property

  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Target

  • Alternative Names
  • NGF; Beta-NGF; HSAN5; NGFB; PG110; ABT-110

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Humanized Antibody

CAT Product Name Application Type
TAB-111 Anti-Human NGF Recombinant Antibody (Tanezumab) ELISA, FuncS, Inhib IgG2
TAB-686CL Anti-Human NGF Therapeutical Antibody (PG110) FuncS Antibody
TAB-501MZ Anti-Human NGF Recombinant Antibody (αD11. H67) ELISA Humanized antibody
TAB-501MZ-S(P) Anti-Human NGF Recombinant Antibody scFv Fragment (αD11. H67) ELISA, IRMA, RIA, IHC Humanized antibody
TAB-501MZ-F(E) Anti-Human NGF Recombinant Antibody Fab Fragment (αD11. H67) ELISA, IRMA, RIA, IHC Humanized antibody

Human Antibody

CAT Product Name Application Type
TAB-244 Anti-Human HNGF Recombinant Antibody Neut, ELISA, IF, IP, FuncS, FC, ICC IgG4 - kappa
TAB-488MZ-F(E) Human Anti-NGF Recombinant Antibody; Fab Fragment (TAB-488MZ-F(E)) ELISA Human Fab
TAB-489MZ-F(E) Human Anti-NGF Recombinant Antibody; Fab Fragment (TAB-489MZ-F(E)) ELISA Human Fab
TAB-512MZ-F(E) Human Anti-NGF Recombinant Antibody; Fab Fragment (TAB-512MZ-F(E)) ELISA, RIA, FC Human Fab
TAB-513MZ-F(E) Human Anti-NGF Recombinant Antibody; Fab Fragment (TAB-513MZ-F(E)) ELISA, RIA, FC Human Fab

scFv Fragment Antibody

CAT Product Name Application Type
PSBL-659 Human Anti-NGF Recombinant Antibody (clone APE1531); scFv Fragment WB, FuncS Human scFv
HPAB-N0190-YC-S(P) Human Anti-NGF Recombinant Antibody (clone NOV009YC); scFv Fragment ELISA Human scFv
HPAB-N0191-YC-S(P) Human Anti-NGF Recombinant Antibody (clone G11-H2L2); scFv Fragment ELISA, FuncS Human scFv
HPAB-1351-FY-F(E) Human Anti-NGF Recombinant Antibody; Fab Fragment (HPAB-1351-FY-F(E)) ELISA, Neut Human Fab
HPAB-1792-FY-F(E) Human Anti-NGF Recombinant Antibody; Fab Fragment (HPAB-1792-FY-F(E)) ELISA, IHC Human Fab

Fab Fragment Antibody

CAT Product Name Application Type
PFBC-234 Human Anti-NGF Recombinant Antibody (clone APE1551); Fab Fragment ELISA, WB Human Fab
FAMAB-0027-YC-F(E) Rat Anti-NGF Recombinant Antibody (clone G 24); Fab Fragment WB Rat Fab
FAMAB-0028-YC-F(E) Rat Anti-NGF Recombinant Antibody (clone G 30); Fab Fragment WB, ICC, FuncS Rat Fab
PFBC-401 Human Anti-NGF Recombinant Antibody (clone MEDI578); Fab Fragment ELISA, IHC Human Fab
HPAB-0718-FY-S(P) Mouse Anti-NGF Recombinant Antibody (clone AB020); Fab Fragment ELISA Mouse Fab

Chimeric Antibody

CAT Product Name Application Type
TAB-509MZ Human Anti-NGF Recombinant Antibody (TAB-509MZ) ELISA Chimeric (mouse/human) IgG
TAB-510MZ Human Anti-NGF Recombinant Antibody (TAB-510MZ) ELISA, FuncS Chimeric (mouse/human) IgG
TAB-509MZ-S(P) Mouse Anti-NGF Recombinant Antibody; scFv Fragment (TAB-509MZ-S(P)) ELISA Mouse scFv
TAB-509MZ-F(E) Human Anti-NGF Recombinant Antibody; Fab Fragment (TAB-509MZ-F(E)) ELISA Chimeric (mouse/human) Fab
TAB-510MZ-F(E) Human Anti-NGF Recombinant Antibody; Fab Fragment (TAB-510MZ-F(E)) ELISA Chimeric (mouse/human) Fab

Mouse Antibody

CAT Product Name Application Type
TAB-500MZ-S(P) Anti-Human NGF Recombinant Antibody scFv Fragment (MNAC13) ELISA, IRMA, RIA, IHC
TAB-502MZ-S(P) Anti-Dog NGF Recombinant Antibody scFv Fragment (NV-01) SDS-PAGE
TAB-503MZ-S(P) Mouse Anti-NGF Recombinant Antibody; scFv Fragment (TAB-503MZ-S(P)) ELISA Mouse scFv
TAB-504MZ-S(P) Mouse Anti-NGF Recombinant Antibody; scFv Fragment (TAB-504MZ-S(P)) ELISA Mouse scFv
TAB-505MZ-S(P) Mouse Anti-NGF Recombinant Antibody; scFv Fragment (TAB-505MZ-S(P)) ELISA Mouse scFv

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0852MZ Chicken Anti-NGF Polyclonal IgY ELISA Chicken antibody
BRD-1134MZ Chicken Anti-Beta NGF Polyclonal IgY ELISA, WB, IHC Chicken antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1764CQ Recombinant Mouse Anti-NGF Antibody (CBL293) Neut IgG1
NEUT-1765CQ Recombinant Mouse Anti-NGF Antibody (12A29) ELISA, Neut IgG1
NEUT-1766CQ Recombinant Mouse Anti-NGF Antibody (M85-2B) ELISA, Neut, WB IgG2b, κ
NEUT-1767CQ Recombinant Mouse Anti-Ngf Antibody (27/21) ELISA, Neut IgG1
NEUT-1769CQ Recombinant Mouse Anti-NGF Antibody (AS18) Neut IgG1

Blocking Antibody

CAT Product Name Application Type
NEUT-1768CQ Recombinant Mouse Anti-NGF Antibody (aD11) IF, BL, ELISA, IHC IgG1, κ
NEUT-1772CQ Recombinant Mouse Anti-NGF Antibody (25623.1) Dot, ELISA, Inhib IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2439 Hi-Affi™ Recombinant Rabbit Anti-NGF Monoclonal Antibody (DS2439AB) WB, ICC, IHC-P, IHC-P IgG

Recombinant Antibody

CAT Product Name Application Type
FAMAB-0028YC Rat Anti-NGF Recombinant Antibody (clone G 30) WB, ICC, FuncS Rat IgG2a
HPAB-1799LY Human Anti-NGF Recombinant Antibody (HPAB-1799LY) ELISA, Neut, FC Humanized IgG
PABC-401 Human Anti-NGF Recombinant Antibody (clone MEDI578) FuncS, ELISA, IHC Human IgG1
MRO-1094-CN Recombinant Rabbit Anti-NGF Monoclonal Antibody (CBACN-402) WB, IF, IHC Rabbit IgG
HPAB-0385-WJ Mouse Anti-NGF Recombinant Antibody (HPAB-0385-WJ) ELISA, FC, FuncS Mouse IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-025ML Afuco™ Anti-NGF ADCC Recombinant Antibody (Frunevetmab), ADCC Enhanced ELISA, IHC, FC, IP, IF, Inhib ADCC enhanced antibody
AFC-TAB-031ML Afuco™ Anti-NGF ADCC Recombinant Antibody (Ranevetmab), ADCC Enhanced ELISA, IHC, FC, IP, IF, Inhib ADCC enhanced antibody
AFC-TAB-111 Afuco™ Anti-NGF ADCC Recombinant Antibody (Tanezumab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-110 Afuco™ Anti-NGF Recombinant Antibody (AFC-TAB-110), ADCC Enhanced FC, IP, ELISA, Neut, FuncS, IF Human IgG1, κ

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
WBWestern Blot

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