Recombinant shark antibody specifically binds to Plasmodium falciparum AMA1, expressed in Chinese Hamster Ovary cells(CHO).
Figure 1 V(NAR)s 12Y-1 and 12Y-2 are specific for P. falciparum AMA1.
ELISA comparison of binding of affinity purified proteins 12Y-1 (black) and 12Y-2 (grey) to lysozyme, AMA1, -amylase, and Tom70.
Figure 2 V(NAR)s 12Y-1 and 12Y-2 are specific for P. falciparum AMA1.
BIAcore sensorgrams showing binding of varying concentrations (685, 342, 171, 85 nM) of monomeric VNAR protein 12Y-1 to immobilized AMA1 protein.
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