Anti-Human PDGFRB Antibody (IMC-2C5), Research Grade Biosimilar (CAT#: TAB-706CL)
Recombinant Human monoclonal antibody expressed in CHO binding to Human PDGFRB. IMC-2C5 binds to both human and mouse PDGFRβ. And it is involved in the treatment of a broad range of human cancers.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Inhib
Figure 1 IMC-2C5 antibody inhibits tumor growth as a monotherapy agent in xenograft models.
Shen, J., Vil, M. D., Prewett, M., Damoci, C., Zhang, H., Li, H., ... & Bassi, R. (2009). Development of a fully human anti-PDGFRβ antibody that suppresses growth of human tumor xenografts and enhances antitumor activity of an anti-VEGFR2 antibody. Neoplasia (New York, NY), 11(6), 594.
FuncS
Figure 2 IMC-2C5 enhances the antitumor activity of an anti-VEGFR2 antibody, DC101.
Athymic nude mice bearing xenografted tumors of 200 to 300 mm size were randomized and divided into four treatment groups (n = 12 per group) and were treated by i.p. injections three times a week with USP saline, IMC-2C5 (40 mg/kg), DC101 (40 mg/kg), or IMC-2C5 plus DC101 (40 mg/kg each).
Shen, J., Vil, M. D., Prewett, M., Damoci, C., Zhang, H., Li, H., ... & Bassi, R. (2009). Development of a fully human anti-PDGFRβ antibody that suppresses growth of human tumor xenografts and enhances antitumor activity of an anti-VEGFR2 antibody. Neoplasia (New York, NY), 11(6), 594.
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- Antibody
- Species Reactivity
- Human
- Applications
- Inhib, FuncS
- Related Disease
- Solid Tumors
Product Property
- Purity
- >90% assessed by SDS-PAGE
- Storage
- Short Term Storage: 4°C
Long Term Storage: -20°C
Applications
- Application Notes
- This antibody has been tested for use in Functional Assay and Inhibition. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "PDGFRB"
Select a product category from the dropdown menu below to view related products.
Please select product type
Human Antibody Products
Neutralizing Antibody Products
Rabbit Monoclonal Antibody Products
Fab Antibody Products
IgG Antibody Products
ADCC Enhanced Antibody Products
ScFv Antibody Products
Antibody Magnetic Beads
ScFv-Fc Chimera Products
Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0988CL | Human Anti-PDGFRB Recombinant Antibody (TAB-0988CL) | ELISA | Human IgG |
| TAB-0989CL | Human Anti-PDGFRB Recombinant Antibody (TAB-0989CL) | ELISA | Human IgG |
| TAB-0990CL | Human Anti-PDGFRB Recombinant Antibody (TAB-0990CL) | ELISA | Human IgG |
| TAB-0991CL | Human Anti-PDGFRB Recombinant Antibody (TAB-0991CL) | ELISA | Human IgG |
| TAB-0988CL-S(P) | Human Anti-PDGFRB Recombinant Antibody; scFv Fragment (TAB-0988CL-S(P)) | ELISA | Human scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for TAB-706CL. Click the button above to contact us or submit your feedback about this product.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-706CL, RRID: AB_3111985)
Copy citation
Popular products with customers
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, WB
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: FuncS, Inhib, IP, ELISA
Application: SPR, Inhib, FuncS
Application: ELISA, FuncS, Neut, IF, WB, EM, Inhib, IHC
Application: ELISA, FC
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
