Human Anti-PDGFRB scFv-Fc Chimera (VS-0325-FY47) (CAT#: VS-0325-FY47)
Anti-PDGFRβ scFv-Fc is a fusion protein that combines the antigen-binding ability of a single-chain variable fragment (scFv) with the effector functions of an immunoglobulin's fragment crystallizable (Fc) region. The antibody demonstrates promising anti-tumor activity in vivo and represents a potential therapeutic advancement for cancer and AMD.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line ASC TERT1
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to the Golgi apparatus & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28499/1774_C4_13_cr5950fa3646972_selected.jpg
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to the Golgi apparatus & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28499/1774_C4_13_cr5950fa3646972_selected.jpg
Figure 2 Testis
(Pachytene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Peritubular cells Staining: High Intensity: Strong Quantity: 75%-25% Spermatogonia cells Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_4_6.jpg
(Pachytene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Peritubular cells Staining: High Intensity: Strong Quantity: 75%-25% Spermatogonia cells Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_4_6.jpg
Figure 3 Placenta
(Decidual cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_2_7.jpg
(Decidual cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_2_7.jpg
Figure 4 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_B_9_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_B_9_5.jpg
Figure 5 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_9_4.jpg
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_9_4.jpg
Figure 6 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_8_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_8_5.jpg
Figure 7 RNA cell line category: Group enriched (ASC diff, ASC TERT1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113721-PDGFRB
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113721-PDGFRB
Specifications
- Immunogen
- Soluble PDGFRβ-Fc.
- Host Species
- Human
- Type
- Human IgG1, scFv-Fc
- Specificity
- Human PDGFRB
- Species Reactivity
- Human
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- beta-type platelet-derived growth factor receptor, CD140B, PDGF-R-beta, PDGFR-beta, PDGFR1
- Gene ID
- 5159
- UniProt ID
- P09619
- Long Name
- Platelet-derived growth factor receptor beta
- Sequence Similarities
- Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
- Cellular Localization
- Cell membrane; Cytoplasmic vesicle; Lysosome; Membrane
- Post Translation Modifications
- Disulfide bond, Glycoprotein, Phosphoprotein
- Protein Refseq
- NP_001341945.1; NP_001341946.1; NP_002600.1
- Function
- Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "PDGFRB"
Select a product category from the dropdown menu below to view related products.
Please select product type
Human Antibody Products
Neutralizing Antibody Products
Rabbit Monoclonal Antibody Products
Fab Antibody Products
IgG Antibody Products
ADCC Enhanced Antibody Products
ScFv Antibody Products
Antibody Magnetic Beads
ScFv-Fc Chimera Products
Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-706CL | Anti-Human PDGFRB Antibody (IMC-2C5), Research Grade Biosimilar | Inhib, FuncS | Antibody |
| TAB-0988CL-F(E) | Human Anti-PDGFRB Recombinant Antibody; Fab Fragment (TAB-0988CL-F(E)) | ELISA | Human Fab |
| TAB-0989CL-F(E) | Human Anti-PDGFRB Recombinant Antibody; Fab Fragment (TAB-0989CL-F(E)) | ELISA | Human Fab |
| TAB-0990CL-F(E) | Human Anti-PDGFRB Recombinant Antibody; Fab Fragment (TAB-0990CL-F(E)) | ELISA | Human Fab |
| TAB-0991CL-F(E) | Human Anti-PDGFRB Recombinant Antibody (TAB-0991CL-F(E)); Fab Fragment | ELISA | Human Fab |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for VS-0325-FY47. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, IHC
Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
![Figure 2 Anti-Human CD19 Recombinant Antibody Fab Fragment [TAB-1611CL-F(E)] in HPLC](https://img.creativebiolabs.net/productimages/COA-TAB-1611CL-F(E)-2.png)
Application: Depletion, FuncS
Application: Neut, Inhib, FC, ELISA
-2-1.png)
Application: ELISA
Application: WB, ELISA, FuncS, Inhib, PK, IP, SPR
Application: ELISA, Inhib, FuncS
Application: ELISA, IHC, IF, IP
Application: ELISA, Inhib, FuncS
Application: EM, ELISA, ICC, IHC-Fr, IHC-P, WB
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
