CytoStream™ Rabbit Anti-PDGFRB Recombinant Antibody (VS13-YC884)
CAT#: VS13-YC884
The CytoStream™ Rabbit Anti-PDGFRB Recombinant Antibody is specific for human, mouse and rat PDGFRB. PDGFRB encodes a tyrosine kinase receptor affecting cell growth and cardiovascular development, implicated in disorders like myeloproliferative syndromes through chromosomal translocation events. The anti-PDGFRB antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/1000).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line ASC TERT1
Immunofluorescent staining of human cell line ASC TERT1 shows localization to the Golgi apparatus & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/28499/1774_C4_13_cr5950fa3646972_selected.jpg
Normal Tissue
Figure 2 Testis
Pachytene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Peritubular cells Staining: High Intensity: Strong Quantity: 75%-25% Spermatogonia cells Staining: Low Intensity: Moderate
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_4_6.jpg
Normal Tissue
Figure 3 Placenta
Decidual cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_2_7.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_B_9_5.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_8_5.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (ASC diff, ASC TERT1)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113721-PDGFRB
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Specifications
- Immunogen
- Recombinant human PDGF Receptor beta, aa 961-1106.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat PDGFRB
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC-P, ICC, IF, FC
- Conjugate
- NONE
- Related Disease
- Kosaki Overgrowth Syndrome and Premature Aging Syndrome, Penttinen Type
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/2000
Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
Flow cytometry (FC): 1/1000
Immunofluorescence (IF-tissue): 1/200
Immunofluorescence (IF-cell): 1/100
mImmunohistochemistry (IHC): 1/1500-1/2000
Target
- Alternative Names
- Platelet Derived Growth Factor Receptor Beta; Platelet-Derived Growth Factor Receptor, Beta Polypeptide; Beta-Type Platelet-Derived Growth Factor Receptor; Platelet-Derived Growth Factor Receptor 1; CD140 Antigen-Like Family Member B; PDGF-R-Beta; EC 2.7.10.1; PDGFR-Beta; PDGFR-1; PDGFR1; PDGFR; Platelet-Derived Growth Factor Receptor Beta;
- Gene ID
- 5159
- UniProt ID
- P09619
- Long Name
- Platelet Derived Growth Factor Receptor Beta
- Sequence Similarities
- Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
- Cellular Localization
- Cell membrane; Cytoplasmic vesicle; Lysosome; Membrane
- Protein Refseq
- NP_001341945.1; NP_001341946.1; NP_002600.1
- Function
- Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "PDGFRB"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0988CL | Human Anti-PDGFRB Recombinant Antibody (TAB-0988CL) | ELISA | Human IgG |
| TAB-0989CL | Human Anti-PDGFRB Recombinant Antibody (TAB-0989CL) | ELISA | Human IgG |
| TAB-0990CL | Human Anti-PDGFRB Recombinant Antibody (TAB-0990CL) | ELISA | Human IgG |
| TAB-0991CL | Human Anti-PDGFRB Recombinant Antibody (TAB-0991CL) | ELISA | Human IgG |
| TAB-0988CL-F(E) | Human Anti-PDGFRB Recombinant Antibody; Fab Fragment (TAB-0988CL-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1850CQ | Recombinant Rat Anti-Pdgfrb Antibody (APB5) | FC, FuncS, Neut | IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2638 | Hi-Affi™ Recombinant Rabbit Anti-PDGFRB Monoclonal Antibody (DS2638AB) | WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0281CQ | Human Anti-PDGFRB Recombinant Antibody (clone 1B3) | ELISA, FC, WB, Neut | Human IgG |
| MRO-2356-CN | Recombinant Rabbit Anti-PDGFRB (phosphorylated Tyr740) Monoclonal Antibody (CBACN-645) | WB, IF | Rabbit IgG |
| HPAB-S0105-YC | Mouse Anti-PDGFRB Recombinant Antibody (clone muM4TS.11) | ELISA, Neut | Mouse IgG |
| HPAB-S0106-YC | Human Anti-PDGFRB Recombinant Antibody (clone HuM4TS.11) | ELISA, Neut | Humanized IgG |
| HPAB-S0107-YC | Mouse Anti-PDGFRB Recombinant Antibody (clone muM4TS.22) | ELISA, Neut | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0281CQ-F(E) | Human Anti-PDGFRB Recombinant Antibody (clone 1B3); Fab Fragment | ELISA, FC, WB, Neut | Human Fab |
| HPAB-S0105-YC-F(E) | Mouse Anti-PDGFRB Recombinant Antibody (clone muM4TS.11); Fab Fragment | ELISA, Neut | Mouse Fab |
| HPAB-S0106-YC-F(E) | Human Anti-PDGFRB Recombinant Antibody (clone HuM4TS.11); Fab Fragment | ELISA, Neut | Humanized Fab |
| HPAB-S0107-YC-F(E) | Mouse Anti-PDGFRB Recombinant Antibody (clone muM4TS.22); Fab Fragment | ELISA, Neut | Mouse Fab |
| HPAB-S0108-YC-F(E) | Human Anti-PDGFRB Recombinant Antibody (clone HuM4TS.22); Fab Fragment | ELISA, Neut | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0281CQ-S(P) | Human Anti-PDGFRB Recombinant Antibody (clone 1B3); scFv Fragment | ELISA, FC, WB, Neut | Human scFv |
| HPAB-S0105-YC-S(P) | Mouse Anti-PDGFRB Recombinant Antibody (clone muM4TS.11); scFv Fragment | ELISA, Neut | Mouse scFv |
| HPAB-S0106-YC-S(P) | Human Anti-PDGFRB Recombinant Antibody (clone HuM4TS.11); scFv Fragment | ELISA, Neut | Humanized scFv |
| HPAB-S0107-YC-S(P) | Mouse Anti-PDGFRB Recombinant Antibody (clone muM4TS.22); scFv Fragment | ELISA, Neut | Mouse scFv |
| HPAB-S0108-YC-S(P) | Human Anti-PDGFRB Recombinant Antibody (clone HuM4TS.22); scFv Fragment | ELISA, Neut | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-448CQ | Afuco™ Anti-PDGFRB Recombinant Antibody (AFC-TAB-448CQ), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | Human IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY209 | AbPlus™ Anti-PDGFRB Magnetic Beads (CBACN-438) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY27 | Human Anti-PDGFRB scFv-Fc Chimera (VS-0125-FY27) | Inhib | Human IgG1, scFv-Fc |
| VS-0325-FY47 | Human Anti-PDGFRB scFv-Fc Chimera (VS-0325-FY47) | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1599 | Anti-PDGFRB Immunohistochemistry Kit | IHC | |
| VS-0525-XY5278 | Anti-Mouse PDGFRB Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC588 | Recombinant Anti-PDGFRB Vesicular Antibody, EV Displayed (VS-0425-YC588) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC143 | Recombinant Anti-PDGFRB (3rd domain x 4th domain) Biparatopic Antibody, Tandem scFv (Clone muM4TS.22 x Clone muM4TS.11) | ELISA, Neut | Tandem scFv |
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