Mouse Anti-PRLR Recombinant Antibody (clone A8)

Name: Mouse Anti-PRLR Recombinant Antibody (clone A8)
SKU: PABZ-179
Rating: 5 (1 reviews)

CAT#: PABZ-179

Recombinant Mouse Antibody (A8) is capable of binding to PRLR. The A8 is displayed in bivalent format by fusion to the pIII coat protein of M13 phage.

Published Data Gene Expression

Figure 1 Inhibition of sAB binding by hGH or PRL using phage ELISA.

Both hGH (left panel) and PRL (right panel) inhibit the interaction between phage-displayed sABs and hPRL-R in a concentration dependent manner.

Rizk, S. S., Kouadio, J. L. K., Szymborska, A., Duguid, E. M., Mukherjee, S., Zheng, J., ... & Kossiakoff, A. A. (2015). Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling. Cell Communication and Signaling, 13(1), 1.

Figure 2 sAB inhibition of hPRL-R in T47D breast cancer cells.

a-b Fluorescence microscopy images of cells treated with 100 nM cy5-hPRL (a) or cy5-hGH (b) in the presence of each sAB. All panels represent two merged channels; blue: DAPI nuclear stain, red: cy5. c A Stat5 phospholyration luciferase reporter assay of T47D cells in the presence or absence of hPRL and hPRL-R sABs. A sAB against bacterial maltose binding protein (MBP) was used as a negative control. d Western blot detection of the time-dependent inhibition of hPRL-R signaling by hPRL-R sABs.

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RNA Expression Figure 1 RNA cell line category: Cell line enriched (T-47d)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113494-PRLR/subcellular

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Specifications

Immunogen
Human prolactin receptor

Host Species
Mouse

Type
Mouse IgG

Specificity
Human PRLR

Species Reactivity
Human

Clone
A8

Applications
ELISA, Neut, WB

Product Property

Purity
>95% as determined by SDS-PAGE and HPLC analysis

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
PRLR; prolactin receptor; HPRL; MFAB; hPRLrI; hPRL receptor; secreted prolactin binding protein;

Gene ID
5618

UniProt ID
P16471

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - PABZ-179.pdf

MSDS

MSDS - PABZ-179.pdf

COA

Certificate of Analysis Lookup

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PABL-198	Mouse Anti-PRLR Recombinant Antibody (clone CBL11Q)	WB, ELISA, FuncS	Mouse IgG
PABL-682	Mouse Anti-PRLR Recombinant Antibody (clone sAB A8)	ELISA	Mouse IgG
MOB-0450CT	Recombinant Mouse anti-Human PRLR Monoclonal antibody (U5)	ELISA, WB
HPAB-0036-CN	Human Anti-PRLR Recombinant Antibody (HPAB-0036-CN)	WB, ELISA, IHC, FC	Chimeric (mouse/human) IgG
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CAT	Product Name	Application	Type
PSBL-198	Mouse Anti-PRLR Recombinant Antibody (clone CBL11Q); scFv Fragment	WB, ELISA, FuncS	Mouse scFv
PSBL-676	Mouse Anti-PRLR Recombinant Antibody (clone sAB A8); scFv Fragment	ELISA	Mouse scFv
HPAB-0029-CN-S(P)	Human Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-0029-CN-S(P))	WB, ELISA, IHC, FC	Human scFv
HPAB-0030-CN-S(P)	Human Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-0030-CN-S(P))	WB, ELISA, IHC, FC	Human scFv
HPAB-0031-CN-S(P)	Mouse Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-0031-CN-S(P))	WB, ELISA, IHC, FC	Mouse scFv

CAT	Product Name	Application	Type
PSBZ-179	Mouse Anti-PRLR Recombinant Antibody (clone A8); scFv Fragment	ELISA, Neut, WB	Mouse scFv
HPAB-0029-CN-F(E)	Human Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-0029-CN-F(E))	WB, ELISA, IHC, FC	Human Fab
HPAB-1600-FY-S(P)	Human Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-1600-FY-S(P))	FC, WB, ELISA	Human scFv
HPAB-1601-FY-S(P)	Human Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-1601-FY-S(P))	FC, WB, ELISA	Human scFv
HPAB-1602-FY-S(P)	Human Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-1602-FY-S(P))	FC, WB, ELISA	Human scFv

CAT	Product Name	Application	Type
TAB-1064CL	Human Anti-PRLR Recombinant Antibody (TAB-1064CL)	FC	Human IgG
TAB-1067CL	Human Anti-PRLR Recombinant Antibody (TAB-1067CL)	ELISA	Human IgG2
TAB-1064CL-S(P)	Human Anti-PRLR Recombinant Antibody (TAB-1064CL-S(P)); scFv Fragment	FC	Human scFv
TAB-1067CL-S(P)	Human Anti-PRLR Recombinant Antibody; scFv Fragment (TAB-1067CL-S(P))	ELISA	Human scFv
TAB-1064CL-F(E)	Human Anti-PRLR Recombinant Antibody (TAB-1064CL-F(E)); Fab Fragment	FC	Human Fab

CAT	Product Name	Application	Type
TAB-1065CL	Mouse Anti-PRLR Recombinant Antibody (TAB-1065CL)	ELISA, FuncS	Mouse IgG
TAB-1065CL-S(P)	Mouse Anti-PRLR Recombinant Antibody; scFv Fragment (TAB-1065CL-S(P))	ELISA	Mouse scFv
TAB-1065CL-F(E)	Mouse Anti-PRLR Recombinant Antibody; Fab Fragment (TAB-1065CL-F(E))	ELISA	Mouse Fab

CAT	Product Name	Application	Type
TAB-1066CL	Human Anti-PRLR Recombinant Antibody (TAB-1066CL)	ELISA	Humanized IgG
TAB-1066CL-S(P)	Human Anti-PRLR Recombinant Antibody; scFv Fragment (TAB-1066CL-S(P))	ELISA	Humanized scFv
TAB-1066CL-F(E)	Human Anti-PRLR Recombinant Antibody; Fab Fragment (TAB-1066CL-F(E))	ELISA	Humanized Fab

CAT	Product Name	Application	Type
NEUT-1881CQ	Recombinant Mouse Anti-PRLR Antibody (CBL154)	Neut, WB	IgG1
NEUT-1882CQ	Recombinant Mouse Anti-PRLR Antibody (CBL359)	Neut, WB	IgG1
NEUT-1883CQ	Recombinant Mouse Anti-PRLR Antibody (6G8)	Neut, WB	IgG1

CAT	Product Name	Application	Type
NEUT-1884CQ	Recombinant Mouse Anti-PRLR Antibody (T6)	BL, FC, ICC, IF, IHC, IP, WB	IgG2a
NEUT-1885CQ	Recombinant Mouse Anti-PRLR Antibody (U5)	BL, FC, ICC, IF, IHC, IHC-Fr, IHC-P, IP, WB	IgG1

CAT	Product Name	Application	Type
MOR-2867	Hi-Affi™ Recombinant Rabbit Anti-PRLR Monoclonal Antibody (DS2867AB)	WB, IHC-P, ICC, IF	IgG

CAT	Product Name	Application	Type
VS-0724-XY40	Mouse Anti-Prlr Agonistic Antibody (VS-0724-XY40)	Agonistic assays	Mouse IgG2a

CAT	Product Name	Application	Type
VS-0425-YC375	Recombinant Anti-PRLR Vesicular Antibody, EV Displayed (VS-0425-YC375)	ELISA, FC, Neut, Cell-uptake

CAT	Product Name	Application
VS-0525-XY5714	Anti-PRLR Immunohistochemistry Kit	IHC
VS-0525-XY5715	Anti-Mouse PRLR Immunohistochemistry Kit	IHC
VS-0525-XY5716	Anti-Rat PRLR Immunohistochemistry Kit	IHC
VS-0525-XY5717	Anti-Rabbit PRLR Immunohistochemistry Kit	IHC

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