SmartAb™ Recombinant Anti-PRLR pH-dependent Antibody (VS-0825-YC287)
CAT#: VS-0825-YC287
The anti-PRLR pH-dependent antibody (VS-0825-YC287) is a pH-responsive antibody engineered to target human, Cynomolgus, mouse, and rat PRLR. This pH-switched monoclonal antibody (mAb) was developed by incorporating histidine residues into its variable regions, which results in pH-biased binding to PRLR. By leveraging the natural pH variations in different tissues and cellular compartments, this pH-responsive antibody facilitates precise targeting of PRLR on cells and tissues. The Prolactin Receptor (PRLR) is a cytokine receptor for the hormone prolactin. It is involved in lactation, reproduction, and mammary gland development, and its expression is also found in some breast cancers.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enriched (T-47d)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113494-PRLR/subcellular
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Specifications
- Immunogen
- Recombinant human prolactin receptor (aa 25-234, ECD).
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human, Cynomolgus, Mouse and Rat PRLR
- Species Reactivity
- Human, Cynomolgus, Mouse, Rat
- Applications
- WB, ELISA, IHC, FC
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95%, determined by SDS-PAGE and SEC-HPLC
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- For short-term storage, keep it at 4°C for up to two weeks. For long-term storage, divide the solution into aliquots and freeze them at -20°C or below.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "PRLR"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-198 | Mouse Anti-PRLR Recombinant Antibody (clone CBL11Q) | WB, ELISA, FuncS | Mouse IgG |
| HPAB-0029-CN | Human Anti-PRLR Recombinant Antibody (HPAB-0029-CN) | WB, ELISA, IHC, FC | Human IgG |
| HPAB-0030-CN | Human Anti-PRLR Recombinant Antibody (HPAB-0030-CN) | WB, ELISA, IHC, FC | Human IgG |
| HPAB-0031-CN | Mouse Anti-PRLR Recombinant Antibody (HPAB-0031-CN) | WB, ELISA, IHC, FC | Mouse IgG |
| HPAB-0032-CN | Mouse Anti-PRLR Recombinant Antibody (HPAB-0032-CN) | WB, ELISA, IHC, FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBZ-179 | Mouse Anti-PRLR Recombinant Antibody (clone A8); Fab Fragment | ELISA, Neut, WB | Mouse Fab |
| HPAB-1600-FY-F(E) | Human Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-1600-FY-F(E)) | FC, WB, ELISA | Human Fab |
| HPAB-1601-FY-F(E) | Human Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-1601-FY-F(E)) | FC, WB, ELISA | Human Fab |
| HPAB-1602-FY-F(E) | Human Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-1602-FY-F(E)) | FC, WB, ELISA | Human Fab |
| MOB-219YJL-S(P) | Human Anti-PRLR Recombinant Antibody; scFv Fragment (MOB-219YJL-S(P)) | ELISA, FC, Inhib | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBZ-179 | Mouse Anti-PRLR Recombinant Antibody (clone A8); scFv Fragment | ELISA, Neut, WB | Mouse scFv |
| HPAB-0029-CN-F(E) | Human Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-0029-CN-F(E)) | WB, ELISA, IHC, FC | Human Fab |
| HPAB-0030-CN-F(E) | Human Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-0030-CN-F(E)) | WB, ELISA, IHC, FC | Human Fab |
| HPAB-0031-CN-F(E) | Mouse Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-0031-CN-F(E)) | WB, ELISA, IHC, FC | Mouse Fab |
| MOB-219YJL-F(E) | Human Anti-PRLR Recombinant Antibody; Fab Fragment (MOB-219YJL-F(E)) | ELISA, FC, Inhib | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1064CL | Human Anti-PRLR Recombinant Antibody (TAB-1064CL) | FC | Human IgG |
| TAB-1067CL | Human Anti-PRLR Recombinant Antibody (TAB-1067CL) | ELISA | Human IgG2 |
| TAB-1064CL-S(P) | Human Anti-PRLR Recombinant Antibody (TAB-1064CL-S(P)); scFv Fragment | FC | Human scFv |
| TAB-1064CL-F(E) | Human Anti-PRLR Recombinant Antibody (TAB-1064CL-F(E)); Fab Fragment | FC | Human Fab |
| TAB-1067CL-F(E) | Human Anti-PRLR Recombinant Antibody; Fab Fragment (TAB-1067CL-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1065CL | Mouse Anti-PRLR Recombinant Antibody (TAB-1065CL) | ELISA, FuncS | Mouse IgG |
| TAB-1065CL-S(P) | Mouse Anti-PRLR Recombinant Antibody; scFv Fragment (TAB-1065CL-S(P)) | ELISA | Mouse scFv |
| TAB-1065CL-F(E) | Mouse Anti-PRLR Recombinant Antibody; Fab Fragment (TAB-1065CL-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1066CL | Human Anti-PRLR Recombinant Antibody (TAB-1066CL) | ELISA | Humanized IgG |
| TAB-1066CL-S(P) | Human Anti-PRLR Recombinant Antibody; scFv Fragment (TAB-1066CL-S(P)) | ELISA | Humanized scFv |
| TAB-1066CL-F(E) | Human Anti-PRLR Recombinant Antibody; Fab Fragment (TAB-1066CL-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1881CQ | Recombinant Mouse Anti-PRLR Antibody (CBL154) | Neut, WB | IgG1 |
| NEUT-1882CQ | Recombinant Mouse Anti-PRLR Antibody (CBL359) | Neut, WB | IgG1 |
| NEUT-1883CQ | Recombinant Mouse Anti-PRLR Antibody (6G8) | Neut, WB | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1884CQ | Recombinant Mouse Anti-PRLR Antibody (T6) | BL, FC, ICC, IF, IHC, IP, WB | IgG2a |
| NEUT-1885CQ | Recombinant Mouse Anti-PRLR Antibody (U5) | BL, FC, ICC, IF, IHC, IHC-Fr, IHC-P, IP, WB | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2867 | Hi-Affi™ Recombinant Rabbit Anti-PRLR Monoclonal Antibody (DS2867AB) | WB, IHC-P, ICC, IF | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-XY40 | Mouse Anti-Prlr Agonistic Antibody (VS-0724-XY40) | Agonistic assays | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC375 | Recombinant Anti-PRLR Vesicular Antibody, EV Displayed (VS-0425-YC375) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5714 | Anti-PRLR Immunohistochemistry Kit | IHC | |
| VS-0525-XY5715 | Anti-Mouse PRLR Immunohistochemistry Kit | IHC | |
| VS-0525-XY5716 | Anti-Rat PRLR Immunohistochemistry Kit | IHC | |
| VS-0525-XY5717 | Anti-Rabbit PRLR Immunohistochemistry Kit | IHC |
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