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PRLR

Anti-PRLR Products
- Human Anti-PRLR Recombinant Antibody (HPAB-1602-FY) (HPAB-1602-FY)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: Inhib, Neut
- Human Anti-PRLR Recombinant Antibody (MOB-219YJL) (MOB-219YJL)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: ELISA, FC, Inhib
- Human Anti-PRLR Recombinant Antibody (HPAB-1600-FY) (HPAB-1600-FY)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: FC, Inhib
- Human Anti-PRLR Recombinant Antibody (HPAB-1601-FY) (HPAB-1601-FY)
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- Species Reactivity: Human, Mouse
- Type: Human IgG1
- Application: Inhib, Neut
- Human Anti-PRLR Recombinant Antibody (HPAB-0035-CN) (HPAB-0035-CN)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: WB, ELISA, IHC, FC
- Human Anti-PRLR Recombinant Antibody (HPAB-0036-CN) (HPAB-0036-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: WB, ELISA, IHC, FC
- Human Anti-PRLR Recombinant Antibody (HPAB-0037-CN) (HPAB-0037-CN)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: WB, ELISA, IHC, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: FC, ICC, IF, IHC
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA, FuncS
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Neut, WB
- Mouse Anti-PRLR Antibody (clone sAB A8), mRNA (PABL-682-mRNA)
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- Species Reactivity: Human
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- Species Reactivity: Human, Mouse
- Type: Human IgG2
- Application: ELISA
- Human Anti-PRLR Recombinant Antibody (VS-0723-WK112) (VS-0723-WK112)
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- Derivation: Chimeric (rabbit/human)
- Species Reactivity: Human
- Type: Chimeric (rabbit/human) IgG1
- Application: FC
- Recombinant Human Anti-PRLR Antibody (clone Rolinsatamab) (VS-0923-FY256)
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- Species Reactivity: Human
- Type: Human IgG1, kappa
- Application: Inhib
- Mouse Anti-Prlr Agonistic Antibody (VS-0724-XY40) (VS-0724-XY40)
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- Species Reactivity: Rat
- Type: Mouse IgG2a
- Application: Agonistic assays
- Human Anti-PRLR Recombinant Antibody (HPAB-0029-CN) (HPAB-0029-CN)
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- Species Reactivity: Human, Mouse, Rat, Cynomolgus monkey
- Type: Human IgG
- Application: WB, ELISA, IHC, FC
- Human Anti-PRLR Recombinant Antibody (HPAB-0030-CN) (HPAB-0030-CN)
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Human IgG
- Application: WB, ELISA, IHC, FC
- Mouse Anti-PRLR Recombinant Antibody (HPAB-0031-CN) (HPAB-0031-CN)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA, IHC, FC
- Mouse Anti-PRLR Recombinant Antibody (HPAB-0032-CN) (HPAB-0032-CN)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA, IHC, FC
- Mouse Anti-PRLR Recombinant Antibody (HPAB-0033-CN) (HPAB-0033-CN)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA, IHC, FC
- Human Anti-PRLR Recombinant Antibody (HPAB-0034-CN) (HPAB-0034-CN)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: WB, ELISA, IHC, FC
- Recombinant Mouse Anti-PRLR Antibody (CBL154) (NEUT-1881CQ)
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- Species Reactivity: Human
- Type: IgG1
- Application: Neut, WB
- Recombinant Mouse Anti-PRLR Antibody (CBL359) (NEUT-1882CQ)
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- Species Reactivity: Human
- Type: IgG1
- Application: Neut, WB
- Recombinant Mouse Anti-PRLR Antibody (6G8) (NEUT-1883CQ)
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- Species Reactivity: Human
- Type: IgG1
- Application: Neut, WB
- Recombinant Mouse Anti-PRLR Antibody (T6) (NEUT-1884CQ)
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- Species Reactivity: Human, Mouse, Rat, Sheep
- Type: IgG2a
- Application: BL, FC, ICC/IF, IHC, IP, WB
- Recombinant Mouse Anti-PRLR Antibody (U5) (NEUT-1885CQ)
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- Species Reactivity: Human, Mouse, Pig, Rat, Horse, Primate, Rabbit, Sheep
- Type: IgG1
- Application: BL, FC, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
- Human Anti-PRLR Recombinant Antibody; Fab Fragment (TAB-1066CL-F(E)) (TAB-1066CL-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA
- Human Anti-PRLR Recombinant Antibody; Fab Fragment (TAB-1067CL-F(E)) (TAB-1067CL-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Species Reactivity: Human
- Application: ELISA, WB
- Human Anti-PRLR Recombinant Antibody (TAB-1066CL) (TAB-1066CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA
- Human Anti-PRLR Recombinant Antibody (TAB-1067CL) (TAB-1067CL)
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- Species Reactivity: Human
- Type: Human IgG2
- Application: ELISA
- Human Anti-PRLR Recombinant Antibody (TAB-1064CL-S(P)); scFv Fragment (TAB-1064CL-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: FC
- Human Anti-PRLR Recombinant Antibody; scFv Fragment (TAB-1066CL-S(P)) (TAB-1066CL-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Human Anti-PRLR Recombinant Antibody; scFv Fragment (TAB-1067CL-S(P)) (TAB-1067CL-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-PRLR Recombinant Antibody (TAB-1064CL-F(E)); Fab Fragment (TAB-1064CL-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC
- Human Anti-PRLR Recombinant Antibody (TAB-1064CL) (TAB-1064CL)
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- Species Reactivity: Human
- Type: Human IgG
- Application: FC
- Human Anti-PRLR Recombinant Antibody; Fab Fragment (MOB-219YJL-F(E)) (MOB-219YJL-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, FC, Inhib
- Mouse Anti-PRLR Recombinant Antibody; Fab Fragment (TAB-1065CL-F(E)) (TAB-1065CL-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, Neut, WB
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, Neut, WB
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-PRLR Recombinant Antibody; scFv Fragment (TAB-1065CL-S(P)) (TAB-1065CL-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-PRLR Recombinant Antibody (TAB-1065CL) (TAB-1065CL)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FuncS
- Human Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-1602-FY-F(E)) (HPAB-1602-FY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FC, WB, ELISA
- Human Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-1600-FY-S(P)) (HPAB-1600-FY-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FC, WB, ELISA
- Human Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-1601-FY-S(P)) (HPAB-1601-FY-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FC, WB, ELISA
- Human Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-1602-FY-S(P)) (HPAB-1602-FY-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FC, WB, ELISA
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, FuncS
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, FuncS
- Human Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-0029-CN-S(P)) (HPAB-0029-CN-S(P))
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- Species Reactivity: Human, Mouse, Rat, Cynomolgus monkey
- Type: Human scFv
- Application: WB, ELISA, IHC, FC
- Human Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-0030-CN-S(P)) (HPAB-0030-CN-S(P))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Human scFv
- Application: WB, ELISA, IHC, FC
- Mouse Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-0031-CN-S(P)) (HPAB-0031-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, IHC, FC
- Human Anti-PRLR Recombinant Antibody; scFv Fragment (MOB-219YJL-S(P)) (MOB-219YJL-S(P))
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- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, FC, Inhib
- Human Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-0037-CN-F(E)) (HPAB-0037-CN-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: WB, ELISA, IHC, FC
- Human Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-1600-FY-F(E)) (HPAB-1600-FY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FC, WB, ELISA
- Human Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-1601-FY-F(E)) (HPAB-1601-FY-F(E))
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- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FC, WB, ELISA
- Mouse Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-0031-CN-F(E)) (HPAB-0031-CN-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, IHC, FC
- Mouse Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-0032-CN-F(E)) (HPAB-0032-CN-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, IHC, FC
- Mouse Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-0033-CN-F(E)) (HPAB-0033-CN-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, IHC, FC
- Human Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-0034-CN-F(E)) (HPAB-0034-CN-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA, IHC, FC
- Human Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-0035-CN-F(E)) (HPAB-0035-CN-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: WB, ELISA, IHC, FC
- Human Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-0036-CN-F(E)) (HPAB-0036-CN-F(E))
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: WB, ELISA, IHC, FC
- Mouse Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-0032-CN-S(P)) (HPAB-0032-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, IHC, FC
- Mouse Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-0033-CN-S(P)) (HPAB-0033-CN-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, ELISA, IHC, FC
- Human Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-0034-CN-S(P)) (HPAB-0034-CN-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, IHC, FC
- Human Anti-PRLR Recombinant Antibody; scFv Fragment (HPAB-0035-CN-S(P)) (HPAB-0035-CN-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, IHC, FC
- Human Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-0029-CN-F(E)) (HPAB-0029-CN-F(E))
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- Species Reactivity: Human, Mouse, Rat, Cynomolgus monkey
- Type: Human Fab
- Application: WB, ELISA, IHC, FC
- Human Anti-PRLR Recombinant Antibody; Fab Fragment (HPAB-0030-CN-F(E)) (HPAB-0030-CN-F(E))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Human Fab
- Application: WB, ELISA, IHC, FC
- Anti-PRLR-SMCC-DM1 ADC (ADC-074CL)
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- Target: prolactin receptor (PRLR)
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: maytansinoid DM1 (maytansinoid N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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- Species Reactivity: Human
- Target: PRLR
- Host Animal: Mouse
- Application: ELISA, FC, Neut, Cell-uptake
- Anti-PRLR Immunohistochemistry Kit (VS-0525-XY5714)
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- Species Reactivity: Human
- Target: PRLR
- Application: IHC
- Anti-Mouse PRLR Immunohistochemistry Kit (VS-0525-XY5715)
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- Species Reactivity: Human, Mouse, Rat
- Target: PRLR
- Application: IHC
- Anti-Rat PRLR Immunohistochemistry Kit (VS-0525-XY5716)
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- Species Reactivity: Rat
- Target: PRLR
- Application: IHC
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, IHC-P, ICC/IF
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For Research Use Only. Not For Clinical Use.
This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.
Protein class
Disease related genes, FDA approved drug targets, Human disease related genes
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Endometrial stromal cells, Granulosa cells, Breast glandular cells, Proximal tubular cells, Syncytiotrophoblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (T-47d)
Interaction
Homodimer upon hormone binding. Interacts with SMARCA1. Interacts with GH1. Interacts with CSH. Interacts with NEK3 and VAV2 and this interaction is prolactin-dependent.
Molecular function
Receptor
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